In the US Preventive Services Task Force Evidence Report entitled “Statins for Prevention of Cardiovascular Disease in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force” published in the November 15, 2016, issue of JAMA,1 incorrect data were reported. In the abstract Results, the data reported for cardiovascular mortality should have read “RR, 0.82 [95% CI, 0.71 to 0.94]; I2 = 0%; ARD, –0.20% [95% CI, –0.35% to –0.05%]; I2 = 11%.” In the second paragraph of the “Benefits of Statin Treatment” subsection in the text, the data reported for cardiovascular mortality should have read “RR, 0.82 [95% CI, 0.71 to 0.94]; I2 = 0%; ARD, –0.20% [95% CI, –0.35% to –0.05%]; I2 = 11%”; 2 paragraphs later, the sentence “For cardiovascular mortality, statistical heterogeneity was present (I2 = 54%), but the estimate was similar using the profile likelihood method (RR, 0.71 [95% CI, 0.55 to 0.88])” should have been deleted; and the text 2 paragraphs later should have read “Funnel plot asymmetry was not observed for outcomes reported in at least 10 trials, except for cardiovascular mortality (P = .049 for Egger test).” In the first paragraph of the Discussion, the data reported for cardiovascular mortality should have read “RR, 0.82 after 2-6 years [95% CI, 0.71 to 0.94]; I2 = 0%; ARD, –0.20% [95% CI, –0.35% to –0.05%],” and the NNT for cardiovascular death should have been reported as 500. In Table 3, “Key Question 1a” section, “Summary of Findings” column, the data reported for cardiovascular mortality should have read “RR, 0.82 [95% CI, 0.71-0.94]; I2 = 0%; ARD, –0.20%; NNT, 500.” Incorrect data also appeared in Figure 3 and the online supplement. This article was corrected online.
Reference
- 1.Chou R, Dana T, Blazina I, Daeges M, Jeanne TL. Statins for prevention of cardiovascular disease in adults: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2016;316(19):2008-2024. doi: 10.1001/jama.2015.15629 [DOI] [PubMed] [Google Scholar]
