In the original article, there was a mistake in Figure 1 and Figure 5 as published. Figures 1E and Figure 5F were wrongly placed. The corrected Figure 1 and Figure 5 appears below.
Figure 1.
NK cells co-culture inhibited tumor progression of pancreatic cancer both in vitro and in vivo. (A,B) CCK-8 assay showed cell viability of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (C) Colony formation assay showed cell proliferation of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (D,E) Transwell assays showed cell migratory and invasive ability of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (F,G) PANC-1 cells were implanted into the flank of mice (n = 4 each group), without (NK cell−) or with co-injection of natural killer cells (NK cell+), respectively, followed by growth curve evaluation on the indicated day after injection. (H–J) Representative in vivo images showed tumor colonization in the lungs of mice (n = 5 each group) following tail vein injection of PANC-1 cells, without (NK cell−) or with co-injection of natural killer cells (NK cell+), respectively, H&E staining of lung sections of mice (metastatic nodules were indicated by yellow arrow, 200×) and incidence of lung metastasis in mice following tail vein injection of the respective PANC-1 cells. The data represent the mean ± SD from three independent experiments. **P < 0.01; ***P < 0.001, two-way ANOVA for (A,B,G), χ2 test for j, Student's t-test for others.
Figure 5.
MiR-3607-3p suppressed proliferation, migration and invasion of pancreatic cancer cells. (A) Mia PaCa-2 and PANC-1 cells were transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC), miR-3607-3p expression levels were quantified by qRT-PCR analysis. (B,C) CCK-8 assay showed cell viability of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). (D) Colony formation assay showed cell proliferation of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). (E,F) Transwell assays showed cell migratory and invasive ability of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). The data represent the mean ± SD from three independent experiments. **P < 0.01; ***P < 0.001. Two-way ANOVA for b and c, Student's t-test for others.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.