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. 2020 Jan 23;6(2):312. doi: 10.1021/acscentsci.0c00021

Retraction of “Targeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)”

Dhanusha A Nalawansha, Stacey-Lynn Paiva, Diane N Rafizadeh, Mariell Pettersson, Liena Qin, Craig M Crews
PMCID: PMC7047427  PMID: 32123750

The authors retract this article after further experiments resynthesizing compounds ENDTAC-1 and ENDTAC-neg were unable to reproduce the presented findings on small molecule-directed targeting of extracellular proteins for degradation via the lysosome.

The original Article was published on May 9, 2019, and retracted on January 23, 2020.


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