Table 1.
Characteristics of the Cohort
| Variables | Median [IQR] or N (%) |
|---|---|
| Age, years | 63 [59–66] |
| Female, n (%) | 15 (60%) |
| Caucasian, n (%) | 16 (64%) |
| African-American, n (%) | 9 (36%) |
| Body mass index, kg/m2 | 26.4 [22.6–30.2] |
| Cancer Type | |
| Lung | 15 (60%) |
| Breast | 10 (40%) |
| Time since Cancer Diagnosis, years | 2.4 [1.1–3.9] |
| Prior chemotherapy | 21 (84%) |
| Time since completion of chemotherapy, years | 1.5 [0.5–3.0] |
| Time since completion of Radiotherapy, years | 1.8 [0.4–3.6] |
|
Hormonal modulating therapy (Breast cancer only) |
7 (28%) |
| MCRD, Gy | 5.4 [3.7–14.7] |
| C-reactive protein, mg/L | 3.0 [1.7–6.9] |
| %APMHR | 93 [78–102] |
| LVEF, % | 52 [47–61] |
| Doppler echo e’ velocity (cm/sec) | 7.6 [7.0–9.6] |
| Delta LVOT VTI CO (L/min) | 1.6 [1.5–1.9] |
Data are listed as n (%) or median (interquartile range). Abbreviations: kg/m2 Kilograms per meter squared, MCRD Mean cardiac radiation dose, Gy Gray units, mg/L Milligrams per liter, %APMHR Percentage of age-predicted maximal heart rate, LVEF Left-ventricular ejection fraction, e’ Doppler early diastolic mitral annular velocity, cm/sec Centimeters per second, LVOT VTI CO Left-ventricular outflow tract velocity time integral cardiac output with exercise, L/min Liters per minute.