Table 1.
Patients type | Number | PTX3 polymorphism | HR/OR (95% CI) | p Value | Reference |
---|---|---|---|---|---|
HSCT | 268 | +281A/G SNP | 2.92(1.69–5.05) | <0.001 | [8] |
+734A/C SNP | 2.62(1.52–4.54) | <0.001 | |||
Haplotype h2/h2 | 3.08(1.47–6.44) | 0.003 | |||
HSCT | 112 | +281A/G SNP | 0.61(0.20–1.92) | 0.4 | [60] |
+734A/C SNP | 0.70(0.25–1.94) | 0.49 | |||
Haplotype h2/h2 | 0.65(0.21–2.06) | 0.47 | |||
HSCT | 2609 | +281A/G SNP | 1.33(1.09–1.64) | 0.005 | [55] |
+281A/G SNP | 1.54(1.02–2.34) | 0.039 | |||
+734A/C SNP | 1.82(1.11–5.34) | 0.017 | |||
Lung Transplant | 102 | Haplotype h2/h2 | 6.69(1.57–28.5) | 0.01 | [58] |
SOT | 1101 | +281A/G SNP | 2.29(1.04–5.03) | 0.04 | [56] |
+734A/C SNP | 3.18(1.45–6.98) | 0.004 | |||
Haplotype h2/h2 | 2.43(1.11–5.34) | 0.03 | |||
COPD | 173 | +1449A/G | 5.94(2.31–15.31) | 0.0004 | [57] |
+281A/G SNP | 1.44(0.44–4.73) | 0.52 | |||
+734A/C SNP | 1.86(0.19–18.65) | 0.49 |
Haplotype h2/h2 refers to the +281 A/G - +734 A/C: G-A/G-A.