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. 2020 Feb 8;48(1):1–8. doi: 10.1080/12298093.2020.1722576

Table 1.

PTX3 SNP polymorphism and IPA.

Patients type Number PTX3 polymorphism HR/OR (95% CI) p Value Reference
HSCT 268 +281A/G SNP 2.92(1.69–5.05) <0.001 [8]
+734A/C SNP 2.62(1.52–4.54) <0.001
Haplotype h2/h2 3.08(1.47–6.44) 0.003
HSCT 112 +281A/G SNP 0.61(0.20–1.92) 0.4 [60]
+734A/C SNP 0.70(0.25–1.94) 0.49
Haplotype h2/h2 0.65(0.21–2.06) 0.47
HSCT 2609 +281A/G SNP 1.33(1.09–1.64) 0.005 [55]
+281A/G SNP 1.54(1.02–2.34) 0.039
+734A/C SNP 1.82(1.11–5.34) 0.017
Lung Transplant 102 Haplotype h2/h2 6.69(1.57–28.5) 0.01 [58]
SOT 1101 +281A/G SNP 2.29(1.04–5.03) 0.04 [56]
+734A/C SNP 3.18(1.45–6.98) 0.004
Haplotype h2/h2 2.43(1.11–5.34) 0.03
COPD 173 +1449A/G 5.94(2.31–15.31) 0.0004 [57]
+281A/G SNP 1.44(0.44–4.73) 0.52
+734A/C SNP 1.86(0.19–18.65) 0.49

Haplotype h2/h2 refers to the +281 A/G - +734 A/C: G-A/G-A.