Figure 5.

Expression analysis using qRT-PCR of twelve key transcriptomes (a) and seven key cytokines (b) in hMDMs of 12 healthy participants infected with M. smegmatis, M. bovis BCG or M. tb R179 as compared to uninfected hMDMs. (*) depicts significant (p < 0.05) expression.

Abbreviations: BCG = Bacillus Calmette–Guerin, hMDMs = human monocyte-derived macrophages, IFIT1 = interferon-induced protein with tetracopeptide, MX = interferon-induced GTP binding protein, IFI = interferon-induced protein, ISG = interferon-stimulated gene, RSAD = radical s-adenosyl methionine domain-containing protein, EIF2AK2 = eukaryotic translation initiation factor 2 alpha kinase 2, TRIB3 = trible homolog, MTA = metastasis-associated protein.