Table 5.

Top regulator effect networks in hMDMs after infection with mycobacteria with respect to 19 potential DEGs.

Pathway	p-Value	Overlap (%)
Interferon signaling	9.51E-08	11.1%
Cytokines mediated communication between immune cells	8.03E-08	7.4%
Pattern Recognition Receptors in recognition of bacteria and viruses	3.43E-07	2.9%
Hypercytokinemia/hyperchemokinemia in the Pathogenesis	4.87E-06	7%
Hematopoiesis from pluripotent stem cells	6.08E-05	6.2%

Abbreviations: hMDMs, human monocyte derived macrophages; DEGs, differentially expressed gene. The data were analyzed through the use of IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuitypathway-analysis).