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. 2020 Mar 2;9(3):30. doi: 10.1038/s41389-020-0214-3

Fig. 3. Ppp1r8−/ livers are less sensitive to DEN-induced hepatocellular carcinoma.

Fig. 3

a Representative picture of CTR and LKO livers 10 months after a single intraperitoneal injection of DEN (25 mg/kg) in male mice of 14 days. b H&E stainings of the DEN-treated livers. Scale bar, 100 µm; T, tumor tissue. c The tumor surface area in DEN-treated livers was quantified on H&E-stained sections. The data are expressed as means ± SD (n = 7). d Number of tumors, as detected in on H&E sections (n = 8). All Data are expressed as means ± SD. *p < 0.05; **p < 0.01 (unpaired Student’s t-test).