Figure 1.

Schematic illustration of the preparation and in vivo application of the GO-collagen tissue engineering chamber in a rat groin model. Graphene oxide (GO) and collagen were dissolved, blended and injected into molds to obtain GO-collagen scaffolds with disc shape and hollow cylindrical shape. After the cross-linking process, GO-collagen scaffolds were fabricated to make a tissue engineering chamber. Then, the BMSCs-gelatin grafts were encased in the GO-collagen chamber and implanted into the rat groin area, with vessels traversing through the graft.