TABLE 6.
Cox Proportional Hazards Multivariate Analysis of Overall Survival
| P-value | HR | 95% CI | |
|---|---|---|---|
| Survival after primary resection | |||
| Time to reoperation (mo) | <.001 | 0.931 | 0.887-0.931 |
| Interval bevacizumab | .025 | 3.187 | 1.083-3.187 |
| Sarcoma present at reoperation | .055 | 4.816 | 0.984-4.816 |
| Treatment effect present at reoperation | .172 | 1.162 | 0.431-1.162 |
| GTR (primary resection) | .861 | 1.486 | 0.623-1.486 |
| Age at recurrence | .92 | 1.022 | 0.981-1.022 |
| Survival after first reoperation | |||
| Interval bevacizumab | .001 | 2.391 | 1.418-4.034 |
| Sarcoma present at reoperation | .002 | 3.532 | 1.592-7.838 |
| Time from prior XRT (mo) | .008 | 0.987 | 0.977-0.997 |
| Treatment effect present | .04 | 0.609 | 0.38-0.979 |
| GTR (recurrence) | .561 | 1.137 | 0.738-1.752 |
| Age at recurrence | .674 | 0.996 | 0.977-1.015 |
CI, confidence interval; GTR, gross total resection; HR, hazard ratio; XRT, radiation therapy.