Zoonotic approach to Shiga toxin-producing Escherichia coli: integrated analysis of virulence and antimicrobial resistance in ruminants and humans – ERRATUM

During the proofing stage for the above article, Table 3 was modified incorrectly. It should have appeared as below:

Table 3.

Resistance (%) and distribution of MICs for the 106 ruminant STEC and 36 human STEC (O111/O157) isolates.

Antimicrobial class	Antimicrobial agent	Source	% Resistancea	No. of isolates at the indicated MIC (mg/l)
				0.015	0.03	0.06	0.12	0.25	0.5	1	2	4	8	16	32	64	128	256	512	1024
Aminoglycoside	Gentamicin	Ruminants	0.0						83	20	3
		Humans	2.8							35					1
β-Lactam	Ampicillin	Ruminants	2.8								17	85	1				3
		Humans	13.9								16	14	1			5
Cephalosporin 3rd	Cefotaxime	Ruminants	0.0					106
		Humans	0.0							36
Cephalosporin 3rd	Ceftazidime	Ruminants	0.0						106
		Humans	0.0							36
Quinolone	Nalidixic acid	Ruminants	0.0									106
		Humans	5.6								33	1				2
(Fluoro)quinolone	Ciprofloxacin	Ruminants	0.0	35	71
		Humans	0.0					36
Sulfonamide	Sulfamethoxazoleb	Ruminants	2.8										33	64	6					3
Folate pathway inhibitor	Trimethoprim	Ruminants	2.8					72	21	9	1					3
Folate pathway inhibitor / Sulfonamide	Trimethoprim/ Sulfamethoxazolec	Humans	16.7							30				6
Carbapenem	Meropenem	Ruminants	0.0		105	1
	Imipenem	Humans	0.0					35	1
	Ertapenem	Humans	0.0						36
Glycylcycline	Tigecycline	Ruminants	0.0					99	7
Macrolide	Azithromycinb	Ruminants	0.0								1	54	50	1
Miscellaneous	Chloramphenicol	Ruminants	0.0										102	4
Polymyxin	Colistin	Ruminants	0.0							105	1
Tetracycline	Tetracycline	Ruminants	2.8								48	53	2				3
β-Lactam + β-lactamase inhibitor	Amoxicillin/clavulanic	Humans	2.8d								30	3	2	1
Cephalosporin 2nd	Cefuroxime	Humans	0.0									36
Cephalosporin 2nd	Cefoxitin	Humans	0.0									32	4
Cephalosporin 4th	Cefepime	Humans	0.0							36
Aminoglycoside	Tobramycin	Humans	2.8d							35			1
Organophosphonate	Fosfomycin	Humans	0.0											36
Nitrofuran	Nitrofurantoin	Humans	0.0											32	4

White fields denote range of dilutions tested for each antimicrobial agent. MICs equal to or above the range are given as the concentration closest to the range and indicated in bold. MICs equal to or lower than the lowest concentration tested are given as the lowest tested concentration. Vertical lines indicate cut-off values: EUCAST epidemiological cut-offs (for ruminant isolates) are represented by thicker lines; CLSI clinical cut-offs (for human isolates) in thin lines, dashed for intermediate and continued for resistant.

^aAll resistant isolates belonged to serotype O157:H7.

^bNo cut-off value given by EUCAST; reference as indicated by double vertical lines were used.

^cTrimethoprim/Sulfamethoxazole cut-off values are expressed as Trimethoprim concentration (range 1:19–16:304).

^dIntermediate resistance.