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. 2020 Mar 6;9(3):giaa014. doi: 10.1093/gigascience/giaa014

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3: — Introgression at the GOLM1-NAA35 locus. (a) rIBD values in a 2-Mb region harboring the GOLM1-NAA35gene. The brown dashed line indicates the 5% threshold line, and the GOLM1-NAA35 region is indicated by grey dashed lines. (b) Genetic differentiation index (F_ST) between French Large White (FLW) and European wild boar (EWB) or South Chinese (SCN) pigs. (c) Haplotype heat map in the GOLM1-NAA35 region. Major and minor alleles in FLW pigs are indicated by beige and light blue, respectively. (d) Haplotype network in the GOLM1-NAA35 region. Each circle represents a haplotype, and the size of the circle is proportional to the haplotype frequency. The line width and length represent the difference between haplotypes. Different colors represent pigs from different geographical regions. AWB: Asian (Chinese) wild boars; ECN: East Chinese pig; EUD: European domestic pig; NCN: North Chinese pig; SWCN: Southwest Chinese pig. (e) Selection signals in the GOLM1-NAA35 region by XP-EHH analysis between FLW and other Large White pigs. The brown dashed line indicates the 5% threshold line. (f) Serum interleukin 6 (IL-6) contents of FLW pigs homozygous (QQ) or heterozygous (Qq) for the introgressed GOLM1-NAA35 haplotypes. The Student t-test was used to compute the P-value (P = 0.015).