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Journal of Orthopaedic Surgery and Research logoLink to Journal of Orthopaedic Surgery and Research
. 2020 Mar 10;15:101. doi: 10.1186/s13018-020-01625-6

Correction to: miR-21-5p protects IL-1β-induced human chondrocytes from degradation

Hai Zhu 1,#, Xin Yan 2,3,#, Meng Zhang 1, Feng Ji 1, Shouguo Wang 1,
PMCID: PMC7063776  PMID: 32156299

Correction to: J Orthop Surg Res (2019) 14:118

https://doi.org/10.1186/s13018-019-1160-7

Following publication of the original article [1], due to mistakes, the flow chart of miR-21 overexpression, miR-21 inhibitor and miR-21 mimic NC in Fig. 3, and the corresponding histogram need to be replaced. The senescent behavior of miR-21 mimic and miR-21 inhibitor in Fig. 4 will be replaced, accompanying the relative histogram.

Fig. 3.

Fig. 3

Effect of miR-21-5p on OA chondrocytes (a). CCK-8 assay was to quantify viable cells (b). the cells were subjected to FACS analysis to determine the cell apoptosis rate. *P < 0.05 compared with the normal group. #P < 0.05 compared with the OA group

Fig. 4.

Fig. 4

To identify senescent cells, chondrocytes were stained with SA β-gal, and observed under a light microscope (magnification × 100). Values represent the mean ± SD from three independent replicate experiments.*P < 0.05 compared with the normal group. #P < 0.05 compared with the OA group

Footnotes

Hai Zhu and Xin Yan contributed equally to this work.

Reference

  • 1.Zhu H, et al. miR-21-5p protects IL-1β-induced human chondrocytes from degradation. J Orthop Surg Res. 2019;14:118. doi: 10.1186/s13018-019-1160-7. [DOI] [PMC free article] [PubMed] [Google Scholar]

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