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. 2019 Dec 26;23(2):171–181. doi: 10.1007/s11102-019-01020-3

Table 2.

Univariate logistic regression analyses for tight hormonal control defined as GH < 1.0 µg/L and IGF-1 levels within normal ranges

Number of patients Odds ratio [95% CI] p-Value
Baseline
 Age (per 10-year higher age) 88 2.50 [1.46; 4.26] < 0.001
 Sex (women vs men) 88 2.73 [0.95; 7.90] 0.063
 BMI (≥ 25 vs 20–25 kg/m2) 88 0.74 [0.27; 2.06] 0.566
 GH (per 1-μg/L lower level) 88 1.02 [0.98; 1.05] 0.361
 IGF-1 (per 50% lower level ULN) 88 1.22 [0.94; 1.58] 0.132
 TV (per 100-mm3 smaller size) 88 1.02 [0.99; 1.05] 0.125
Week 12
 GH (per 1-μg/L lower level) 84 11.61 [3.12; 43.27] < 0.001
 IGF-1 (per 50% lower level ULN) 85 4.70 [2.05; 10.81] < 0.001
 TV (per 100-mm3 smaller size) 85 1.04 [0.99; 1.08] 0.091
Change-from-baseline to week 12
 GH (per 10% increase) 84 0.78 [0.62; 0.98] 0.030
 IGF-1 (per 10% increase) 85 0.58 [0.42; 0.81] 0.001
 TV (per 10% reduction) 85 1.29 [0.91; 1.83] 0.160

Factors in bold are statistically significant. Data are based on the number of patients with available data for each factor at each timepoint, and with p-values from Chi squared tests