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Tridimensional representation of (A) human H ferritin and (B) Archaeoglobus fulgidus ferritin. Despite the high degree of similarity between the secondary and tertiary structures, A. fulgidus ferritin (AfFt) and human ferritin differ in their quaternary structures. Human ferritin displays a tightly closed spherical shell with octahedral (4-3-2) symmetry; AfFt shows a roughly spherical shell with tetrahedral (2-3) symmetry containing four large pores.
