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. 2020 Feb 23;25(4):991. doi: 10.3390/molecules25040991

Table 4.

Maximum concentration of isothiazolinones admitted in commercial products available in the EU [5,60].

Commercial Products Maximum Admitted Concentration of Biocide
Cosmetics 1 MCI/MI < 15 ppm 3
MI < 100 ppm 4
BIT forbidden 5
OIT forbidden 6
DCOIT forbidden 7
Paints 2, glues 2, detergents 1 MCI/MI < 15 ppm
MI < 300 ppm
BIT < 360 ppm
OIT insufficient data
DCOIT insufficient data
Industrial biocides 2 MI, MCI, and BIT used at high concentrations (e.g., >5000 ppm)
OIT insufficient data
DCOIT insufficient data

1 Labeling is legally required; 2 No labeling required; 3 From April 2016 onwards: forbidden in leave-on cosmetics; 4 Banned from leave-on cosmetics since January 2017; 5 Exceptionally (illegally) presented in cosmetic in the EU market, allowed in cosmetic in the USS and Canada; 6 Exceptionally (illegally) presented in cosmetic in the EU market; 7 Exceptionally (illegally) presented in cosmetic in the EU market.