Table 2.
Effect of D-allulose supplementations for 16 weeks on plasma lipid profiles in C57BL/6J mice fed a high-fat diet.
| ND | HFD | ERY | ALL | |
|---|---|---|---|---|
| FFA (mmol/L) | 0.20 ± 0.00 | 0.20 ± 0.00 | 0.19 ± 0.00 | 0.16 ± 0.00 |
| TG (mg/dL) | 0.86 ± 0.31 | 0.86 ± 0.09 | 0.93 ± 0.31 | 0.81 ± 0.16 |
| Total-C (mmol/L) | 3.56 ± 0.32 | 5.17 ± 1.21 ***a | 4.48 ± 0.80 ab | 3.94 ± 0.32 b |
| HDL-C (mmol/L) | 0.95 ± 0.15 | 1.46 ± 0.34 ***a | 1.15 ± 0.21 a | 0.88 ± 0.13 b |
| Non-HDL-C (mmol/L) | 2.61 ± 0.38 | 3.72 ± 0.93 ***a | 3.33 ± 0.69 a | 2.65 ± 0.39 b |
| ApoA-I (mg/dL) | 31.52 ± 1.88 | 30.25 ± 0.90 a | 26.97 ± 1.18 ab | 25.53 ± 1.56 b |
| ApoB (mg/dL) | 6.03 ± 2.81 | 8.04 ± 2.92 | 6.51 ± 3.05 | 5.87 ± 2.64 |
| ApoA-I/ApoB | 6.54 ± 3.59 | 4.41 ± 2.18 | 5.02 ± 2.52 | 6.09 ± 4.71 |
| HTR 1 | 25.75 ± 4.39 | 28.32 ± 3.58 | 25.92 ± 4.46 | 22.30 ± 2.48 |
| AI 2 | 2.84 ± 0.72 | 2.58 ± 0.45 | 2.96 ± 0.69 | 3.54 ± 0.52 |
Data are mean ± SD. Significant differences between HFD vs ND are indicated; *** p < 0.001; a, b Mean not sharing a common letter are significantly different among the groups at p < 0.05. ND, normal diet (AIN-76); HFD, high-fat diet (AIN-76, 20% fat, 1% cholesterol); ALL, (HFD + 5% D-allulose). FFA, free fatty acid; TG, triglyceride; C, cholesterol; ApoA-I, apolipoprotein A-I; ApoB, apolipoprotein B; non-HDL-C = (Total-C) − (HDL-C); HTR 1, (HDL-C/Total-C) × 100; AI 2, atherogenic index = [(Total-C) − (HDL-C)]/HDL-C.