Table 2.
Specific Effect | Model Used | Results | Reference Number |
---|---|---|---|
Obesogenic Effects/Metabolic Disorders | Murine | BPS caused a transient loss in body weight in one behavioral study, but caused increased body weight via the activation of preadipocytes in all other studies | Kim et al. [33] Boucher et al. [34] Achmed & Atlas [35] Ivry Del Moral et al. [36] |
Sheep | BPS caused adipogenic differentiation in males, while BPA had the same effect in females | Pu et al. [37] | |
human embryonic stem cells | BPS increased cellular expression of adipogenic genes and caused accumulated triglycerides | Wang et al. [38] | |
Clinical/Observational | BPS levels correlated with insulin resistance, albuminuria, irregular vascular function and gestational diabetes mellitus (GDM) | Kataria et al. [39] Zhang et al. [40] |