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. 2020 Feb 4;9(2):357. doi: 10.3390/cells9020357

Figure 1.

Figure 1

Tubulin Polymerization Promoting Protein (TPPP/p25)-derived ultrastructural organization of microtubules. Images of microtubules without or with human recombinant TPPP/p25: (A) control, (B) TPPP/p25-induced microtubule bundling, as visualized by electron microscopy. HeLa cells expressing pEGFP-TPPP/p25 (green): (C) control, (D) aggresome; (E) perinuclear cage; HeLa cells transiently transfected with EGFP-TPPP/p25 (green): (F) different expression levels produce distinct microtubule (red) ultrastructures: (1) alignment to the microtubule network, (2) aggresome formation, (3) perinuclear cage as visualized by immunofluorescence microscopy (selected from [9] and [8]). Scale bar: 100 nm (A,B); 10 μm (C–F).