Table 1.

TPPPs in cancer.

Cancer	TPPP	Level	Level	Other
Pancreatic	TPPP/p25	Protein	Low	High level helps invasion	[74]
Pancreatic	TPPP/p25	RNA	Low		[71]
Pancreatic	TPPP/p25	RNA	Low		[72]
Liver	TPPP/p25	RNA	Low		[73]
Oligodendroglioma	TPPP/p25	Protein	Low		[70]
Lung	TPPP/p25	RNA	Low	5p15.33	[75]
non-small cell Lung	TPPP/p25	DNA		gain of 5p15.33	[76]
Bile duct	TPPP/p25	DNA		gain of 5p15.33	[77]
Bladder	TPPP/p25	DNA		gain of 5p15.33	[78]
HeLa cells	TPPP3	RNA		Depletion by RNAi suppressed cell proliferation	[79]
Lung (Lewis carcinoma)	TPPP3	RNA		Depletion by RNAi inhibits tumor cell growth	[80]
Colorectal	TPPP3	RNA, Protein	High	Knockdown inhibited cell proliferation, migration and invasion; overall survival rate was lower in patients with high expression of TPPP3	[81]
non-small cell Lung	TPPP3	Protein	High	Knockdown by shRNA inhibited cell proliferation in vitro; depletion of TPPP3 inhibited lung cancer growth in vivo	[82]
Lung	TPPP3	Protein	High		[83]
Ovarian	TPPP3	RNA	High	10x overexpression	[84]
Clear cell sarcoma	TPPP3	RNA, Protein	High		[85]
Pancreatic ductal adenocarcinoma	TPPP3	Protein		Higher TPPP3 level indicates long survival	[86]