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Human AVICs express Klotho. (A) Klotho protein is present in human AVICs and is upregulated by matrilin-2 stimulation for 48 h. (B) Klotho mRNA is detectable in human AVICs and increases in a time-dependent manner following matrilin-2 stimulation. Values are means ± SE. n = 3 separate experiments; * P < 0.05 vs. control.
