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. 2020 Jan 29;9(2):320. doi: 10.3390/cells9020320

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Macrophages and dendritic cells are recruited to the sciatic nerves. (A–D) FACS analysis of CD4 (Panel A), CD11c (panel B), MHC II (panel C), F4 80 (panel D) positive cells in contralateral and ipsilateral nerves 5, 9 and 14 days after E0771 cell injection. Data are presented as mean ± S.E.M. (contralateral n = 4–7, ipsilateral n = 5–14), Two-tailed Student t test, * p < 0.05, ** p < 0.01, *** p < 0.001. (E,F) Same as Panel A and B except that cells were determined 19 days after MC57 (panel E) or 10 days after B16-F10 (panel F). (G) Cytokine and chemokine levels were detected by multiplex cytokine/chemokine assay in E0771 (d6), MC57 (d18) and B16-F10 (d9) tumors.