Table 1.

Parameters used in the multiple metabolically healthy obesity definitions.

Parameters Used in the Multiple MHO Definitions	References
CVD diagnosis	[12,55]
Evaluation of insulin sensitivity (determined by euglycemic-hyperinsulinemic clamp, homeostatic model assessment-insulin resistance (HOMA-IR), Matsuda index, insulin suppression test, glucose disposal rate, triglyceride glucose index, and oral glucose tolerance test)	[3,5,6,7,10,11,12,15,16,30,31,32,35,38,40,42,46,48,53,56,59,64,68,71,72,74,77,78,79,84,85,86,87,89]
Determination of systolic and diastolic blood pressure (including information on antihypertensive drug treatment)	[5,6,7,9,10,11,12,16,30,31,32,35,38,42,46,48,52,53,54,55,56,57,58,59,61,64,68,69,70,73,75,76,79,80,81,82,83,84,86,87,88,89]
Circulating lipid profile (apolipoprotein B, triglycerides and total-, low density lipoprotein (LDL)-, and HDL-cholesterol as well as triglycerides/HDL-cholesterol, total-cholesterol/HDL-cholesterol, and % of LDL particles with diameter <255 Å; plus data on associated medication treatment)	[3,5,6,7,9,10,11,12,16,30,31,32,35,38,42,46,48,52,53,54,55,56,57,58,59,61,64,68,69,70,71,73,75,76,77,79,80,81,82,83,84,86,87,88,89]
Circulating glucose levels and related parameters (glycated hemoglobin and history/diagnosis of T2DM as well as use of blood glucose lowering agents/T2DM treatment)	[5,6,7,9,10,11,12,16,30,31,32,35,38,42,46,48,52,53,55,56,57,58,59,61,64,68,69,70,73,75,76,79,80,81,82,83,84,86,87,88,89]
Circulating insulin levels	[12,16,32,54,56,68]
Circulating inflammatory profile (C-reactive protein, fibrinogen and white blood cell count)	[6,11,12,16,31,32,42,52,53,54,56,59,68,75,77,80,83,86,89]
Uric acid levels	[12,16]
Waist circumference	[6,10,11,16,30,31,32,35,52,53,56,61,64,68,69,79,81,82,88,89]
Assessment of cardiorespiratory fitness	[56,89]