Table 2.

Upregulated genes (fold change ≥ 5) in ring-stage IT4^CSAEC40° parasites compared to ring-stage IT4^CSAEC37° parasites (padj < 0.01).

Gene Name	Gene ID	Read Counts (RNAseq)
		IT4CSAEC37°	IT4CSA-EC40°	Fold Change	Reference
knob-associated histidine-rich protein (kahrp) * K	PFIT_0201300	0	148657	N/A	[41]
erythrocyte membrane protein 3 (pfemp3) * K	PFIT_0201200	0	21077	N/A	[42]
knob associated heat shock protein 40 (kahsp40) *K	PFIT_0201100	0	14136	N/A	[43]
DnaJ protein *	PFIT_0201000	0	4965	N/A	[44]
PHISTb domain-containing RESA-like protein 1 * K	PFIT_0200900	0	3861	N/A	[44]
rifin	PFIT_0424300	0	2377	N/A
Plasmodium exported protein (hyp9) *	PFIT_0200800	0	388	N/A	[45]
rifin	PFIT_bin10000	9	302	34
Plasmodium exported protein (phista)	PFIT_0423600	7	108	16
ring-infected erythrocyte surface antigen 2	PFIT_1149700	102	1405	14
Plasmodium exported protein (phistb) K	PFIT_0423000	242	2535	10	[46]
glycophorin binding protein K	PFIT_1300400	272	2076	8	[43]
Plasmodium exported protein (phista)	PFIT_0423100	852	5709	7
asparagine-rich antigen, putative	PFIT_0931800	25	158	6
Plasmodium exported protein	PFIT_0725000	789	4099	5
acyl-CoA synthetase K	PFIT_0801900	141	695	5	[46]
virulence-associated protein 1	PFIT_0937100	67	307	5

* Located at the subtelomeric region of chromosome 2; K Associated with knob formation.