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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Biomaterials. 2020 Feb 21;241:119906. doi: 10.1016/j.biomaterials.2020.119906

Fig. 5. Multiple human FerA domains increased the AAV9 transduction by systemic injections.

Fig. 5.

AAV9/luc vectors were incubated with DPBS or hDys-/hMyo-/hOto-FerA domains for 2 h at 4 °C. The complex was injected into the female C57BL/6 mice by systemic administration. At different time points (D1, 3, 9, 14) post AAV application, images were taken for luminescence analysis (A). The average luciferase signal for liver and brain was calculated (B). The gene copy numbers in liver, brain, heart, kidney, and muscle were separately determined (C). The data of each group represent the average and SD from five mice. *** p < 0.001, ** p < 0.01, and *p < 0.05 compared to control mice with AAV9/luc treatment only.