Correction: Vitamin and cofactor acquisition in apicomplexans: Synthesis versus salvage.

VOLUME 295 (2019) PAGES 701–714

After careful observation, it has come to the authors' attention that some abbreviations and cofactors used in Figs. 3 and 4 are incorrect. In Fig. 3, the reaction catalyzed by NAD(+) kinase to convert NAD(+) to NADP(+), uses ATP as the cofactor and not NADH. In Fig. 4, the abbreviations of the enzymes, PPCL and PPCD, have been corrected to PPCS and PPCDC, respectively. Additionally, the cofactors being utilized in the last four reactions were corrected: (i) PPCS uses cysteine and ATP, (ii) PPCDC releases a CO₂ molecule (not SAM), (iii) PPAT consumes an ATP molecule (not NADPH), and (iv) dephospho-CoA kinase utilizes an ATP molecule (not SAM). Further, the branched-chain amino acid, l-valine, does not come from glycolysis, but is instead transported from the extracellular environment. The folate cofactor for 2-dehydropantoate synthesis was also corrected to 5,10-methylene-THF (instead of 5,10-methyl-THF). In the legend for Fig. 4, “PPCL, phosphopantetheine-cysteine ligase” was corrected to “PPCS, phosphopantothenoylcysteine synthetase,” and the correct abbreviation for phosphopantothenoylcysteine decarboxylase is PPCDC. In the text (section on Vitamin B₅), phosphopantetheine-cysteine ligase should be read as “phosphopantothenoylcysteine synthetase.”

Figure 3.

Figure 4.