Skip to main content
Springer Nature - PMC COVID-19 Collection logoLink to Springer Nature - PMC COVID-19 Collection
. 1972;236(5341):78–81. doi: 10.1038/236078a0

Australia Antigen as a Marker of Propagation of the Serum Hepatitis Virus in Liver Cultures

A J ZUCKERMAN 1, PAMELA M BAINES 1, JUNE D ALMEIDA 2
PMCID: PMC7086489  PMID: 4623141

Abstract

ATTEMPTS to isolate the human hepatitis viruses in tissue culture have resulted in a collection of “hepatitis-candidate” viruses, none of which has since been shown to be the causal agent of human hepatitis1. The discovery of Australia antigen provided a specific serological marker of infection with or carriage of the serum hepatitis virus, although the nature of the antigen remains unsettled2.

References

  • 1.Zuckerman AJ. Virus Diseases of the Liver. 1970. p. 46. [Google Scholar]
  • 2.Memorandum: Tests for Australia (hepatitis-associated) antigen and antibody, Bull. Wld Hlth Org., 42, 957 (1970). [PMC free article] [PubMed]
  • 3.Zuckerman AJ. Nature. 1969;223:569. doi: 10.1038/223569a0. [DOI] [PubMed] [Google Scholar]
  • 4.Brighton WD, Taylor PE, Zuckerman AJ. Nature New Biology. 1971;232:57. doi: 10.1038/newbio232057a0. [DOI] [PubMed] [Google Scholar]
  • 5.Coyne, V. E., Millman, I., and Blumberg, B. S., Bacteriol. Proc. (Abstr.), 175 (1971).
  • 6.Baines, P. M., Taylor, P. E., and Zuckerman, A. J., Arch. Ges. Virusforsch. (in the press).
  • 7.Zuckerman AJ. Vox Sang. 1970;19:304. doi: 10.1111/j.1423-0410.1970.tb01530.x. [DOI] [PubMed] [Google Scholar]
  • 8.Zuckerman AJ, Taylor PE. Nature. 1969;223:81. doi: 10.1038/223081a0. [DOI] [PubMed] [Google Scholar]
  • 9.Almeida JD, Waterson AP. Adv. Virus Res. 1969;15:307. doi: 10.1016/S0065-3527(08)60878-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Dane DS, Cameron CH, Briggs M. Lancet. 1970;i:695. doi: 10.1016/S0140-6736(70)90926-8. [DOI] [PubMed] [Google Scholar]

Articles from Nature are provided here courtesy of Nature Publishing Group

RESOURCES