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. 1979;48(1):63–66. doi: 10.1007/BF00691793

Pseudoviral hollow-cored vesicles in multiple sclerosis brain

J Kirk 1
PMCID: PMC7086663  PMID: 506692

Summary

Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyelination. This case demonstrates the need for caution in the interpretation of unusual electron microscopic appearances.

Key words: Acute multiple sclerosis, Virus-like particles, Demyetination, Electron microscopy

References

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