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. 1982;71(4):279–290. doi: 10.1007/BF01315058

A comparative analysis of measles virus RNA by oligonucleotide fingerprinting

J R Stephenson 1, V ter Meulen 1
PMCID: PMC7086895  PMID: 7092572

Summary

Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T1 oligonucleotides from single-stranded, full-length RNA isolated from cytoplasmic nucleocapsids. Although all viruses have oligonucleotides in common, each isolate generated a unique pattern of oligonucleotides. However, no group of oligonucleotides was observed which would allow a differentiation between viruses isolated from acute infections and those isolated from CNS diseases; indicating that probably all measles viruses differ in their nucleotide sequence, regardless of origin.

Keywords: Nucleotide, Infectious Disease, Nucleotide Sequence, Comparative Analysis, Encephalitis

Footnotes

With 3 Figures

References

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