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. 2009 Jun 16;70(1):191–197. doi: 10.1365/s10337-009-1146-4

Table 1.

Factor levels, design matrix and response in the 25 factorial design for screening MAE method

Factor Units Levels
Variable Key Low (−) Middle (0) High (+)
Extraction temperature A °C 50 75 100
Extraction time B Min 1.0 3.5 6.0
Extraction solvent volume C mL 5.0 10.0 15.0
Ethanol percentage D v/v 60 80 100
Microwave power E % 60 80 100
Run A B C D E Response (mg g−1) Run A B C D E Response (mg g−1) Run A B C D E Response (mg g−1)
1 + + + 1.129 13 + + 1.500 25 + + 0.939
2 + 1.500 14 0 0 0 0 0 0.830 26 + 1.501
3 + + 0.718 15 + + 2.050 27 + + + + 0.629
4 + + + + 0.940 16 + + 0.968 28 + + + + 0.750
5 + + + 0.970 17 0 0 0 0 0 0.829 29 + 2.048
6 + + 0.971 18 + + + 1.130 30 + + + 0.940
7 + + + + 0.720 19 + + + 0.970 31 + + + 0.628
8 + + + 0.720 20 + + + 2.050 32 0 0 0 0 0 0.830
9 0 0 0 0 0 0.830 21 + + + 0.748 33 + + 0.748
10 + 0.968 22 + + + 0.729 34 1.500
11 + + + + + 0.628 23 + + 0.940 35 + + 2.049
12 + + 1.128 24 + 0.939 36 + + + + 0.630