Table 1.
Factor | Units | Levels | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Key | Low (−) | Middle (0) | High (+) | ||||||||||||||||
Extraction temperature | A | °C | 50 | 75 | 100 | |||||||||||||||
Extraction time | B | Min | 1.0 | 3.5 | 6.0 | |||||||||||||||
Extraction solvent volume | C | mL | 5.0 | 10.0 | 15.0 | |||||||||||||||
Ethanol percentage | D | % v/v | 60 | 80 | 100 | |||||||||||||||
Microwave power | E | % | 60 | 80 | 100 |
Run | A | B | C | D | E | Response (mg g−1) | Run | A | B | C | D | E | Response (mg g−1) | Run | A | B | C | D | E | Response (mg g−1) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | + | + | − | + | − | 1.129 | 13 | − | − | − | + | + | 1.500 | 25 | + | − | − | + | − | 0.939 |
2 | − | − | − | + | − | 1.500 | 14 | 0 | 0 | 0 | 0 | 0 | 0.830 | 26 | − | − | − | − | + | 1.501 |
3 | + | − | + | − | − | 0.718 | 15 | − | + | − | − | + | 2.050 | 27 | + | + | + | + | − | 0.629 |
4 | + | + | − | + | + | 0.940 | 16 | − | − | + | + | − | 0.968 | 28 | − | + | + | + | + | 0.750 |
5 | − | + | + | − | + | 0.970 | 17 | 0 | 0 | 0 | 0 | 0 | 0.829 | 29 | − | + | − | − | − | 2.048 |
6 | − | − | + | − | + | 0.971 | 18 | + | + | − | − | + | 1.130 | 30 | + | − | − | + | + | 0.940 |
7 | + | − | + | + | + | 0.720 | 19 | − | − | + | + | + | 0.970 | 31 | + | + | + | − | − | 0.628 |
8 | + | − | + | − | + | 0.720 | 20 | − | + | − | + | + | 2.050 | 32 | 0 | 0 | 0 | 0 | 0 | 0.830 |
9 | 0 | 0 | 0 | 0 | 0 | 0.830 | 21 | − | + | + | + | − | 0.748 | 33 | − | + | + | − | − | 0.748 |
10 | − | − | + | − | − | 0.968 | 22 | + | − | + | + | − | 0.729 | 34 | − | − | − | − | − | 1.500 |
11 | + | + | + | + | + | 0.628 | 23 | + | − | − | − | + | 0.940 | 35 | − | + | − | + | − | 2.049 |
12 | + | + | − | − | − | 1.128 | 24 | + | − | − | − | − | 0.939 | 36 | + | + | + | − | + | 0.630 |