Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

Correction to: Scientific Reports 10.1038/srep29179, published online 14 July 2016

This Author Correction corrects the following errors in the Article. The authors neglected to cite a relevant study related to the isolation of the EGS strain of Toxoplasma gondii from amniotic fluid from a congenitally infected Brazilian fetus. As a result, in the Introduction,

“To address these challenges, we characterized the EGS parasite (Fig. 1), isolated in 1994 from amniotic fluid of a congenitally infected Brazilian fetus²⁵, that form cyst-like structures in vitro.”

should read:

“To address these challenges, we characterized the EGS parasite (Fig. 1; ATCC® PRA-396), isolated in 1994 from amniotic fluid of a congenitally infected Brazilian fetus¹ that form cyst-like structures in vitro²⁵.”

In the Results section, under subheading ‘Characterization of EGS strain develops novel in vitro models to test compounds’,

“This AP2 represses bradyzoite to tachyzoite conversion, among other differences (Table 1; Fig. 1c; Supplement A: Box and Figure S2, Supplement B: Excel Table S1).”

should read:

“This AP2 represses tachyzoite to bradyzoite conversion², among other differences (Table 1; Fig. 1c; Supplement A: Box and Figure S2, Supplement B: Excel Table S1).”

In Figure 6d, the incorrect image for transfected EGS was used. The correct Figure 6d appears below as Figure 1.

Figure 1.

.

Finally, in the Discussion section,

“This Apetela 2 plant like transcription factor gene is known to drive tachyzoite switch by repressing bradyzoite genes.”

should read:

“This Apetela 2, plant-like transcription factor gene, AP2IV-4, represses bradyzoite genes during the tachyzoite cell cycle, thereby preventing commitment to the bradyzoite developmental pathway².”