TABLE 2.
Immune markers in stool samples of the study children
| Marker analyzeda | Value for child group |
P value of statistical analysisb
|
||||
|---|---|---|---|---|---|---|
|
Lean (n = 16) |
Obese (n = 20) |
Obese+IR (n = 15) |
Lean vs obese | Lean vs obese+IR | Obese vs obese+IR | |
| IL-6 | 17.8 (12.4–51.8) | 22.2 (4.0–26.1) | 26.4 (11.8–37.3) | 0.226 | 0.925 | 0.149 |
| IFN-γ | 28.5 (19.8–49.2) | 192.5 (91.0–273.4) | 103.8 (52.0–168.7) | <0.001 | 0.007 | 0.055 |
| TNF-α | 9.7 (5.7–21.3) | 7.8 (7.8–10.5) | 33.7 (10.8–70.6) | 0.902 | 0.019 | 0.004 |
| MCP-1 | 7.8 (7.8–7.8) | 35.9 (12.1–57.9) | 21.75 (5.9–49.7) | 0.003 | 0.103 | 0.427 |
a
Values are expressed in nanograms of cytokine per gram of stool and as the medians of respective distributions accompanied by Q1 and Q3 boundaries within parentheses.
b
P values resulting from pairwise comparison between groups using Wilcoxon rank sum test. Statistical difference between pairs of groups was considered when P values were ≤0.05 (bold and underlined). Multiple-testing correction was applied when more than one pairwise comparison was done at once (Benjamini-Hochberg).