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. 2012 Jun 10;49(10):825–828. doi: 10.1007/s13312-012-0194-1

Human coronavirus NL63 in hospitalized children with respiratory infection: A 2-year study from Chongqing, China

Chen Xin 1, Zhang Zhi Yong 1, Li Yan 2, Zhao Xiao Dong 1,✉
PMCID: PMC7096939  PMID: 22728623

Abstract

Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Children’s Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were <1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.

Key words: Acute lower respiratory tract infections, Epidemiology, HCoV-NL63, Respiratory tract virus

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Articles from Indian Pediatrics are provided here courtesy of Nature Publishing Group

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