Skip to main content
NCBI home page
Springer Nature - PMC COVID-19 Collection logoLink to Springer Nature - PMC COVID-19 Collection
. 1978;6(2):71–72. doi: 10.1007/BF01642161

Diarrhea in newborn cynomolgus monkeys infected with human rotavirus

Diarrhöe bei neugeborenen Cynomolgusaffen nach Infektion mit menschlichem Rotavirus

M Majer 1, F Behrens 1, E Weinmann 1, R Mauler 1, G Maass 2, H G Baumeister 2, T Luthardt 3
PMCID: PMC7100795  PMID: 206515

Summary

Of six newborn cynomolgus monkeys (Macaca fascicularis) naturally delivered and normally nursed five developed diarrhea after oral administration of human rotavirus. Virus excretion was observed in the stool of four animals. This virus was transmitted to four out of six other monkeys causing diarrhea in only one animal.

Keywords: Public Health, Internal Medicine, Infectious Disease, Diarrhea, Oral Administration

Literature

  • 1.Gomez-Barreto J., Palmer E.L., Nahmias A.J., Hatch M.H. Acute enteritis associated with reovirus-like agent. J. Am. Med. Ass. 1976;237:1857–1860. [PubMed] [Google Scholar]
  • 2.Middleton P.J., Petric M., Szymanski M.T. Propagation of infantile gastroenteritis virus (orbi-group) in conventional and germfree piglets. Infect. Immun. 1975;12:1276–1280. doi: 10.1128/iai.12.6.1276-1280.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Mebus Ch. A., Wyatt R. G., Sharpee R.L.i, Sereno M.M., Kalica A.R., Kapikian A.Z., Twiehaus M.J. Diarrhea in gnotobiotic calves caused by the reovirus-like agent of human infantile gastroenteritis. Infect. Immun. 1976;14:471–474. doi: 10.1128/iai.14.2.471-474.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Snodgrass D.R., Mandeley C.R., Wells P.W., Angus K.W. Human rotavirus in lambs: Infection and passive protection. Infect. Immun. 1977;16:268–270. doi: 10.1128/iai.16.1.268-270.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Wyatt R.G., Sly D.L., London W.T., Palmer A.E., Kalica A.R., Van-Kirk D.H., Chanock R.M., Kapikian A.Z. Induction of diarrhea in colostrum-deprived newborn rhesus monkeys with the human reovirus-like agent of infantile gastroenteritis. Arch. Virol. 1976;50:17–27. doi: 10.1007/BF01317997. [DOI] [PubMed] [Google Scholar]
  • 6.Bridger, J.C., Wood, G.N.: Neonatal calf diarrhea: Identification of reoviruslike (rotavirus) agent in faeces by immunofluorescence and immune electron microscopy. Br. Vet. J. 131 [PubMed]
  • 7.Kapikian A.Z., Cline W.L., Mebus C.A., Wyatt R.G., Kalica A.R., James H.D., Van-Kirk D., Chanock R.M., Kim H.W. New complement fixation test for the human reovirus-like agent of infantile gastroenteritis. Lancet. 1975;1:1056–1061. doi: 10.1016/s0140-6736(75)91827-9. [DOI] [PubMed] [Google Scholar]
  • 8.Maass G., Baumeister H.G., Freitag N. Viren als Ursache der akuten Gastroenteritis im Säuglings- und Kleinkinderalter. Münch. Med. Wschr. 1977;119:1029–1034. [PubMed] [Google Scholar]
  • 9.Stövesand P., Behrens F., Majer M., Maass G. Seroepidemiological investigations on the epidemiology of human rotavirus infections. Zbl. Bakteriol. 1977;238:16–19. [PubMed] [Google Scholar]
  • 10.Holmes J.H., Mathan M., Bhat P., Albert M. J., Swaminothan S.P., Maiya P.P., Pereira S.M., Baker S.J. Orbiviruses and gastroenteritis. Lancet. 1974;2:658–659. doi: 10.1016/s0140-6736(74)91987-4. [DOI] [PubMed] [Google Scholar]

Articles from Infection are provided here courtesy of Nature Publishing Group

RESOURCES