Zusammenfassung
Leukämiepatienten entwickeln häufig leukämie- oder therapieassoziierte kritische Komplikationen, die eine intensivmedizinische Behandlung nötig machen. Bei vielen dieser Patienten besteht ein kuratives Therapieziel und sie haben die Aussicht auf eine Langzeit- Remission, vorausgesetzt die Phasen der therapieassoziierten Komplikationen können erfolgreich intensivmedizinisch beherrscht werden. Nachfolgend sollen typische Komplikationen bei Leukämiepatienten, die eine intensivmedizinische Therapie erforderlich machen, beziehungsweise für den Leukämiepatienten typische Aspekte bei der Anwendung invasiver Techniken auf der Intensivstation, das Management auf der Intensivstation, die aktuelle Studienlage über intensivmedizinische Maßnahmen bei Leukämiepatienten und ethische Aspekte abgehandelt werden.
Schlüsselwörter: Leukämie, intensivmedizinische Behandlung, Tumorlyse-Syndrom, disseminierte intravasale Gerinnung, Mortalität, respiratorische Insuffizienz
Abstract
Patients with leukemia are prone to critical illness at some time during their disease and their therapy that requires critical care. A number of these patients will have the opportunity to receive curative treatment and have an excellent probability of long-term remission if supported through a crisis. Complications that cause critical illness can be categorized as related to disease or those caused by therapy. The present review is focused on the description of the types of complications requiring intensive care, on specific aspects of the application of critical-care techniques, on organization of the intensive care unit in the context of leukemia and on ethical considerations.
Key words: leukemia, critical care, tumor lysis syndrome, disseminated intravascular coagulation, mortality, respiratory failure
Footnotes
Serie:
Die Notfall- und Intensivtherapie bei hämatologischen und onkologischen Erkrankungen
Herausgegeben von E. Holler und C. Wrede (Regensburg)
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