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. 2010 Jul 16;122(13):441–451. [Article in German] doi: 10.1007/s00508-010-1407-0

Der potentielle Organspender – Evaluierung unter besonderer Berücksichtigung der Herzentnahme

Evaluation of the potential organ donor with special regards to heart donation

Daniel Höfer 1,✉, Arezu Aliabadi 2, Christian Ebner 3, Christoph Hörmann 4, Stephane Mahr 2, Regina Mascherbauer 3, Gerhard Pölzl 5, Albert Reiter 6, Andrä Wasler 7, Thomas Weber 8, Michael Zink 9, Andreas Zuckermann 2, Herwig Antretter 1
PMCID: PMC7102121  PMID: 20628904

Summary

Regarding limited availability of organ donors for heart transplantation, it is necessary to discuss optimal donor evaluation and donor management. In this manuscript general donor-related parameters as well as heart-specific parameters are discussed regarding international literature. In addition, "marginal" donors and in contrast "optimal" donors are defined. Donor management including optimal hemodynamic management and additional specific intensive care aspects are presented. Exact donor evaluation allows for matching the organ to the most suitable recipient and is therefore especially in the context of marginal donors a crucial step within transplantation process.

Keywords: Organ donor, Donor evaluation, Donor management, Marginal donor

Abbreviations:

HTX

Herztransplantation

MAP

mittlerer arterieller Blutdruck

ZVD

zentral venöser Druck

ZVO2

zentral venöse Sauerstoffsättigung

SVO2

gemischt venöse Sauerstoffsättigung

PAWP

pulmonal kapillärer Verschlussdruck

CI

cardiac index

paO2

arterieller Sauerstoffpartialdruck

paCO2

arterieller Kohlendioxydpartialdruck

PEEP

positiver endexpiratorischer Druck

AMV

Atemminutenvolumen

Hb

Hämoglobin

Na+

Serumnatrium

Hk

Hämatokrit

CRP

C-reaktives Protein

KHK

koronare Herzerkrankung

ADH

antidiuretisches Hormon

ECMO

extrakorporale Membranoxygenierung

VAD

ventricular assist device

EKG

Elektrokardiogramm

LV

linker Ventrikel

RV

rechter Ventrikel

LVEDD

linksventrikulärer enddiastolischer Durchmesser

RVEDD

rechtsventrikulärer enddiastolischer Durchmesser

LVEF

linksventrikuläre Auswurffraktion

TAPSE

tricuspid annular plain systolic excursion

ARDS

adult respiratory distress syndrome

CAG

Coronarangiographie

CT

Computertomographie

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