Abstract
A method for preparation of carboxy-protected amino acid conjugates of glycyrrhizinic acid with the use of N-hydroxybenzotriazole, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, and methyl esters of L-amino acids (phenylalanine, tyrosine, leucine, isoleucine, and methionine) in 85–90% yield was developed. The structure of the prepared compounds was confirmed by IR and 13C NMR spectra.
Keywords: glycyrrhizinic acid, amino acids methyl esters, glycopeptides, N-hydroxybenzotriazole, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide
Footnotes
Original Russian Text © L.A. Baltina Jr., A.I. Fairushina, L.A. Baltina, 2016, published in Zhurnal Obshchei Khimii, 2016, Vol. 86, No. 4, pp. 639–642.
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