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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Cancer. 2020 Jan 8;126(7):1576–1584. doi: 10.1002/cncr.32694

Table 4.

Chronic conditions related to cognitive measures among survivors (n=150)

Chronic conditions
Grade 2–4
Verbal reasoning Reading Mathematics Attention variability Verbal learning

β P β P β P β P β P

Cardiovascular −0.06 0.83 0.18 0.27 0.15 0.56 0.24 0.44 0.13 0.59
Respiratory −0.04 0.86 −0.17 0.21 −0.26 0.22 −0.21 0.38 0.15 0.46
Reproductive −0.13 0.52 −0.17 0.15 −0.05 0.79 0.10 0.68 −0.05 0.78
Endocrine 0.10 0.61 −0.04 0.75 −0.02 0.93 −0.20 0.34 −0.05 0.76
Musculoskeletal −0.25 0.35 −0.19 0.25 −0.66 0.01 0.08 0.79 −0.15 0.55
Neurology −0.36 0.16 −0.05 0.77 −0.63 0.02 −1.17 <0.01 −0.10 0.68
Hearing impairment −0.68 <0.01 −0.24 0.13 −0.75 <0.01 0.16 0.61 −0.48 0.05


Chronic conditions
Grade 2–4
Long-term verbal memory Visual memory Working memory Cognitive flexibility Initiation

β P β P β P β P β P

Cardiovascular 0.13 0.62 0.09 0.76 0.01 0.97 −0.29 0.48 −0.29 0.23
Respiratory 0.12 0.58 0.01 0.98 −0.10 0.61 −0.19 0.55 −0.25 0.21
Reproductive 0.12 0.55 0.003 0.99 −0.03 0.85 −0.13 0.67 −0.19 0.30
Endocrine 0.08 0.69 0.15 0.44 −0.05 0.74 0.06 0.83 0.00 1.00
Musculoskeletal 0.05 0.86 −0.47 0.09 −0.18 0.44 −1.07 <0.01 −0.07 0.79
Neurology −0.05 0.86 −0.38 0.16 −0.01 0.95 −0.63 0.10 −0.56 0.02
Hearing impairment −0.66 0.01 −0.40 0.17 −0.32 0.15 −0.56 0.17 −0.17 0.49

Separate models for each cognitive outcome and each organ system. All models adjusted for age at diagnosis and race/ethnicity. β represents the non-standardized coefficient; units: Cognitive measures: z-scores, M=0, SD=1, condition grade 2–4 as compared to grade 0–1. Bold text indicates significant models.