Figure 2.

Selected molecular alterations in primary histiocytic sarcoma (pHS) cases. Genes are listed in the rows and organized by pathway or function. Samples are listed in columns. Site and IG gene rearrangement status are indicated in the top annotation bar. Underlined sample labels indicate a case with a B-cell lymphoma associated mutation or clonal IG gene rearrangement. Annotated focal copy number alterations and translocations were detected by OncoScan and/or verified by fluorescence in situ hybridization or polymerase chain reaction. GI: gastrointestinal tract; LN: lymph node; CNS: central nervous system.