Correction to: Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis

Correction to: J Exp Clin Cancer Res

https://doi.org/10.1186/s13046-019-1321-x

In the original publication of this manuscript [1], the Fig. 6a invasion si-hsa_circ_0058124_2# group (row 2 right and row 3 right) and Fig. 9c TPC-1 clone formation assay control group (row 1 left) were misplaced and need to be revised. The updated figures are shown below.

The authors apologize for the inconvenience that the corrections caused.

Fig. 6.

Hsa_circ_0058124 affects the migration, invasion abilities, and apoptosis of PTC cells in vitro. a Representative images and quantification results of cell migration and invasion abilities of TPC-1 and K1 cells harboring control or hsa_circ_0058124 siRNAs. b Scratch wound assays in hsa_circ_0058124-deficient PTC cells and corresponding controls. c, d Flow cytometry assays showed the rate of apoptosis (c) and the cell cycle distributions (d) in TPC-1 cells transfected with si-NC or si-hsa_circ_0058124. ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001

Fig. 9.

The oncogenic hsa_circ_0058124/NOTCH3/GATAD2A axis in PTC cells. a Expression of Notch3 and GATAD2A in TPC-1 cells at protein level analyzed by western blot, after transfection with the indicated siRNAs. b, c The CCK-8 assays (b) and colony formation assays (c) were used to evaluate the cell growth after transfection with si-hsa_circ_0058124 or co-transfected with si-hsa_circ_0058124 and si-GATAD2A or si-NC in PTC cells. d Transwell assays were applied to evaluate the migration and invasion of PTC cells after transfection with si-hsa_circ_0058124 or co-transfected with si-hsa_circ_0058124 and si-GATAD2A or si-NC. e Immunohistochemistry analysis of GATAD2A protein levels in PTC tissues. Representative images were shown. Scale bar, 100 μm. f Representative images for the expression of GATAD2A in thyroid tumor tissues and normal thyroid tissues are shown with the fraction of samples with antibody staining/protein expressions evaluated as high, medium, low, or not detected based on the blue-scale color coding. Data are presented as the mean ± S.E.M., analyzed using independent samples student’s t-test. ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001