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. 2020 Apr 1;5(2):e00021-20. doi: 10.1128/mSphere.00021-20

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Copyright © 2020 Schnaider et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — dhvar2 and L7F interact with both SUV membrane models. (a and b) Membrane interaction with the two SUV model membrane systems consisting of (a) DOPC/DMPG/ErgS/PDA and (b) DOPE/DMPG/ErgS/PDA (1:0.6:0.4:3) vesicles. PDA color transitions were induced upon peptide membrane activity. EgrSt, ergosterol. (c) Membrane permeabilization of C. albicans by AMPs. The images shown influx of FITC (53) into cells after 6 h of incubation with the indicated peptides at 250 μg/ml. FITC staining (green) indicates compromised fungal membrane integrity. Scale bar, 20 μm.