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. Author manuscript; available in PMC: 2021 Aug 18.
Published in final edited form as: Circulation. 2020 Jun 17;142(7):621–642. doi: 10.1161/CIRCULATIONAHA.120.046361

Figure 3. Intervention effects on cIMT progression plotted against intervention effects on risk for the primary CVD endpoint, according to type of intervention.

Figure 3

The RRs for intercepts as well as P values for heterogeneity of intercept and slope are provided in Figure 4. The areas of the bubbles are proportional to the inverse variance of the log relative risk for the primary CVD endpoint. For purpose of presentation, the graph area was limited to -80 to 80 μm/year on the horizontal axis and 0.25 to 4 on the vertical axis. Trials with point estimates outside of this area are indicated with the symbol x. Abbreviations: cIMT=carotid intima-media thickness. CVD=cardiovascular disease. RR=relative risk.