Skip to main content
NCBI home page
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2000 Mar 10;44(2):351–358. doi: 10.1016/0378-1135(95)00028-9

Control of canine distemper

G Chappuis 1,∗
PMCID: PMC7117223  PMID: 8588329

Abstract

Control of canine distemper can realistically only be achieved by the use of vaccination. The types of vaccine in current use are described, together with some of the problems encountered such as interference by maternal antibodies, and usage in species other than dogs. Modified live viral vaccines, as used for more than thirty years, have proved very effective. Nevertheless there is scope for some improvement in vaccine efficacy and recent developments in genetic recombinant methods are described.

Keywords: Distemper, Dog, Vaccination

References

  • Commission Directive 92/18/EEC of 20 March 1992Off. Journal of the European Communities. 1992 No L 97-1/23 10-4-92. [Google Scholar]
  • Appel M.J.G. Reversion to virulence of attenuated canine distemper virus in vivo and in vitro. J. Gen. Virol. 1978;41:385–393. [Google Scholar]
  • Appel M.J.G. Elsevier; 1987. Canine distemper virus (Chap. 13). Virus Infections of Carnivores; p. 133. [Google Scholar]
  • Appel M.J.G. Immune response to vaccinia virus and recombinant virus products in dogs. Am. J. Vet. Res. 1988;49:1932–1934. [PubMed] [Google Scholar]
  • Baker J.A. Measles vaccine for protection of dogs against canine distemper. JAVMA. 1970;156:1743–1746. [PubMed] [Google Scholar]
  • Blixenkrone-Møller M., Svansson V., Have P., Orvell C., Appel M., Pedersen I.R., Dietz H.H., Henriksen P. Studies on manifestations of canine distemper virus infection in an urban population. Vet. Microbiol. 1993;37:163–173. doi: 10.1016/0378-1135(93)90190-i. [DOI] [PubMed] [Google Scholar]
  • Brooks R. Adverse reactions to canine and feline vaccines. Australian Vet. J. 1991;68:342–344. doi: 10.1111/j.1751-0813.1991.tb03096.x. [DOI] [PubMed] [Google Scholar]
  • Burtonboy S., Charlier P., Hertoghs S., Lobman M., Wiseman A., Woods S. Performance of high titre attenuated canine parvovirus vaccine in pups with maternally derived antibody. Vet. Rec. 1991;124:377–381. doi: 10.1136/vr.128.16.377. [DOI] [PubMed] [Google Scholar]
  • Carpenter J.W., Appel M.J.G., Erickson R.C., Novilla M.N. Fatal vaccine-induced cdv infection in blackfooted ferrets. JAVMA. 1976;169:96–9643. [PubMed] [Google Scholar]
  • Chalmers W.S.K., Baxendale W. A comparison of canine distemper vaccine and measles vaccine for the prevention of canine distemper in young puppies. Vet. Rec. 1994;135:349–353. doi: 10.1136/vr.135.15.349. [DOI] [PubMed] [Google Scholar]
  • Chappuis G., Terré J. Immunisation contre la Maladie de Carré et la Maladie de Rubarth. II - Installation Précoce de l'Immunité. Rec. Med. Vet. 1973;149:177–186. [Google Scholar]
  • Chappuis G., Terré J. Immunisation contre la Maladie de Carré et la Maladie de Rubarth. III - Voie Oculonasale. Voie Orale. Rec. Med. Vet. 1973;149:1451–1461. [Google Scholar]
  • Chappuis G., Terré J., Précausta P. Immunisation contre la maladie de Carré et la maladie de Rubarth. I - La Sérovaccination. Rec. Med. Vet. 1973;149:91–94. [Google Scholar]
  • Chappuis G., Terré J., Brun A., Précausta P. Immunisation contre la Maladie de Carré et la Maladie de Rubarth. IV - Calendrier de Vaccination. Rec. Med. Vet. 1974;150:515–525. [Google Scholar]
  • Chappuis G., Languet B., Duret C., Desmettre P. Dog Rabies Vaccination. The Use of Recombinant Poxvirus by Oral and Parenteral Route. In: Fondation Marcel Mérieux, editor. Proc. of the Symposium on Rabies Control in Asia FMM/WHO; Jakarta April 27–30 1993; 1994. SBN 2-84039-029-9. [Google Scholar]
  • Cornwell H.J.C., Thompson H., Mccandlish I.A.P., Mccartney L., Nash A.S. Encephalitis in dogs associated with a batch of canine distemper vaccine. Vet. Rec. 1988;122:54–59. doi: 10.1136/vr.122.3.54. [DOI] [PubMed] [Google Scholar]; Cornwell H.J.C., Thompson H., Mccandlish I.A.P., Mccartney L., Nash A.S. Encephalitis in dogs associated with a batch of canine distemper vaccine. Vet. Rec. 1988;122:187. doi: 10.1136/vr.122.3.54. [DOI] [PubMed] [Google Scholar]
  • de Vries P., Uytdehaag G.F.C., Osterhaus A.D.M.E. Canine distemper virus ISCOMs but not MV-ISCOMs, protect dogs against CDV infection. J. Gen. Virol. 1988;69:2071–2083. doi: 10.1099/0022-1317-69-8-2071. [DOI] [PubMed] [Google Scholar]
  • Gillespie J.H. The significance of passive immunity and the biological tests used in the study of distemper. JAVMA. 1966;149:623–632. [PubMed] [Google Scholar]
  • Haig D.A. Canine distemper immunization with avianised virus. Onderstepoort. J. Vet. Res. 1956;27:19–53. [Google Scholar]
  • Kieny M.P., Lathe R., Drillien R., Spehner S., Skory D., Schmitt T., Wiktor T., Koprowski H., Lecocq J.P. Expression of Rabies Virus Glycoprotein from a Recombinant Vaccinia Virus. Nature. 1984;312:163. doi: 10.1038/312163a0. [DOI] [PubMed] [Google Scholar]
  • Krakowka S., Olsen R.G., Axthelm M.K., Rice J., Winters K. Canine Parvovirus Infection Potentiates Canine Distemper Encephalitis Attributable to MLV-Vaccine. JAVMA. 1982;180:137–140. [PubMed] [Google Scholar]
  • McClelland R., Gillespie J.H. Canine Immunization. The Cornell Vet. 1966;56:300–304. [PubMed] [Google Scholar]
  • Michel C., Terré J., Soulebot J.P., Desmettre P., Chappuis G., Stellmann C. Vaccinations associées du chien. Comparaison entre vaccinations successives et vaccinations simultanées. Bull. Acad. Vet. 1971;43:277–284. [Google Scholar]
  • Montali R.J., Bartz C.R., Teare J.A., Allen J.T., Appel M.J.G., Bush M. Clinical trial with canine distemper vaccines in exotic animals. JAVMA. 1983;183:1163–1167. [PubMed] [Google Scholar]
  • Norrby E., Utter G., Orvell C., Appel M.J.G. Protection against canine distemper virus in dogs after immunization with isolated fusion protein. J. Virol. 1986;58:536–541. doi: 10.1128/jvi.58.2.536-541.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • Osterhaus A.D.M.E., Visser I.K.G., Vedder E.J., Reijnders P.J.H., Kuiper J., Brugge H.N. Seal vaccination success. Nature. 1989;337:21. doi: 10.1038/337021a0. [DOI] [PubMed] [Google Scholar]
  • Panicali D., Paoletti E. Vol. 79. 1972. Construction of Poxviruses as Cloning Vectors: Insertion of the Thymidine Kinase Gene from Herpes Simplex Virus into the DNA of Infections Vaccinia Virus; p. 4927. (Proc. Nat. Acad. Sci. USA). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • Pastoret P.P., Brochier B., Blancou J., Artois M., Aubert M., Kieny M.P., Lecocq J.P., Languet B., Chappuis G., Desmettre P. Development and deliberate release of a vaccinia-rabies recombinant virus for the oral vaccination of foxes against rabies. In: Binns, Smith, editors. Recombinant Poxvirus. CRC Press; 1992. pp. 163–206. Chapter 5. [Google Scholar]
  • Phillips T.R., Jensen J.L., Rubino M.J., Yang W.C., Schultz R.D. Effects of vaccines on the canine immune system. Can. J. Vet. Res. 1989;53:154–160. [PMC free article] [PubMed] [Google Scholar]
  • Puntoni V. Saggio di vaccinazione anticimurossa preventiva eseguita per mezzo del virus specifico. Ann. Igiene. 1923;33:553. [Google Scholar]
  • Rockborn G. An attennuated strain of canine distemper virus in tissue culture. Nature (London) 1959;184:822. doi: 10.1038/184822a0. [DOI] [PubMed] [Google Scholar]
  • Straw B. Decrease in platelet count after vaccunation with distemper-hepatitis (DH) vaccine. Vet. Med. SAC. 1978;73:725–726. [PubMed] [Google Scholar]
  • Tartaglia J., Taylor J., Cox W.I., Audonnet J.C., Perkus M.E., Radaelli A., De Guili Morghen C., Meignier B., Rivière M., Weinbold K.J., Paoletti E. Novel poxvirus strains as research tools and vaccine vectors. In: Koff W.C., Wong-Staal F., Kennedy R.C., editors. Vol. 3. Marcel Dekker; NY: 1972. pp. 361–378. (Aids Research Reviews). [Google Scholar]
  • Terré J., Chappuis G., Précausta P. Calendrier de vaccination du chien. Rec. Med. Vet. 1978;154:551–557. [Google Scholar]
  • Tizard I. Risks associated with use of live vaccines. JAVMA. 1990;196:1851–1858. [PubMed] [Google Scholar]
  • Visser I.K.G., Vedder E.J., Van De Bildt M.W.G., Orvell C., Barrett T., Osterhaus A.D.M.E. Canine distemper virus ISCOMs induce protection in harbour seals (Phoca vitulina) against phocid distemper but still allow subsequent infection with Phocid Distemper Virus-1. Vaccine. 1992;10:435–438. doi: 10.1016/0264-410x(92)90390-6. [DOI] [PubMed] [Google Scholar]
  • Wild F., Bernard A., Spehner D., Villeval D., Drillien R. Vaccination of mice against canine distemper virus induced encephalitis with vaccinia virus recombinants encoding measles or canine distemper antigens. Vaccine. 1993;11:438–444. doi: 10.1016/0264-410x(93)90285-6. [DOI] [PubMed] [Google Scholar]

Articles from Veterinary Microbiology are provided here courtesy of Elsevier

RESOURCES