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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Development. 2017 Aug 1;144(15):2719–2729. doi: 10.1242/dev.132605

Figure 3. Domain structure of KZFPs.

Figure 3

All KZFPs contain a KRAB domain and an array of zinc fingers. Those are responsible for interacting with the DNA, and in each three amino acids (at positions 6, 3, and -1) are engaged in mediating contacts with DNA. KRAB, Krüppel-associated box; ZF, zinc finger; SCAN, SREZBP, CTfin51, AW-1, and Number 18 cDNA; DUF3669, domain of unknown function 3669.