Table 1.
Minimum Clinically Important Differences of the CAT in Bronchiectasis
| Definition | Result (SD or Mean Change in CAT) | Proposed MCID |
|---|---|---|
| Distribution based | ||
| ½ SD TRIBE cohort | 3.89 | 4 |
| ½ SD validation cohort | 3.91 | 4 |
| Anchor based | ||
| Exacerbation onset | 3.57 | 4 |
| Exacerbation recovery | -4.83 | 5 |
| 4-point change in SGRQ as anchor | 3.43 | 3 |
| 1.3-point change in LCQ as anchor | 3.78 | 4 |
CAT = COPD Assessment Test; LCQ = Leicester Cough Questionnaire; MCID = minimum clinically important difference; SGRQ = St. George’s Respiratory Questionnaire.