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. 2002 Nov 12;6(5):267–269. doi: 10.1016/0166-0934(83)90041-1

Clones of MRC-C cells may be superior to the parent line for the culture of 229E-like strains of human respiratory coronavirus

RJ Phillpotts 1
PMCID: PMC7119661  PMID: 6874877

Abstract

A clone was selected from the MRC-C continuous heteroploid cell line which was significantly better than MRC-C for the culture of human respiratory coronavirus (HCV) 229E, strain LP. Such clones could prove generally useful for the isolation of HCV-229E from clinical specimens, and for the propagation and assay of laboratory adapted strains.

Keywords: cloning, cell line, human respiratory coronavirus

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