Abstract
The quality of drinking water in the United States is among the best in the world; however, waterborne disease outbreaks continue to occur, and many more cases of endemic illness are estimated. Documented waterborne disease outbreaks are primarily the result of technological failures or failure to treat the water (Craun et al. 2006). Current federal regulations require that all surface waters used for a drinking water supply be treated to reduce the level of pathogens so as to reduce the risk of infection to 1:10,000 per year (Regli et al. 1991). To achieve this goal, water treatment must, at a minimum, reduce infectious viruses by 99.99% and protozoan parasites by 99.9% (Regli et al. 2003). If Cryptosporidium concentrations exceed a certain level in the source water, additional reductions are required. This degree of treatment is usually achieved by a combination of physical processes (coagulation, sedimentation, and filtration) and disinfection (chlorination, ozonation). Filtration is essential for the removal of protozoan parasites due to their resistance to chlorination and ozonation at doses normally used in drinking water treatment (Barbeau et al. 2000; Korich et al. 1990; Rennecker et al. 1999). A variance from filtration is allowed in some cases if the watershed is protected and carefully monitored for protozoan pathogens.
Keywords: Gastrointestinal Illness, Waterborne Disease, Heterotrophic Plate Count, Drinking Water Distribution System, Waterborne Pathogen
References
- Abbaszadegan M., LeChevallier M., Gerba C. Occurrence of viruses in US groundwaters. J Am Water Works Assoc. 2003;95:107–120. [Google Scholar]
- Aboytes R., DiGiovanni G., Abrams F.A., Rheinecker C., McElroy W., Shaw N., Lechevallier M.W. Detection of infectious Cryptosporidium in filtered drinking water. J Am Water Works Assoc. 2004;96:88–98. [Google Scholar]
- Addiss D.G., Pond R.S., Remshak M., Juranek D.D., Stokes S., Davis J.P. Reduction of risk of watery diarrhea with point-of-use water filters during a massive outbreak of waterborne Cryptosporidium infection in Milwaukee, Wisconsin. Am J Trop Med. 1993;54:549–553. doi: 10.4269/ajtmh.1996.54.549. [DOI] [PubMed] [Google Scholar]
- Allen M.J., Edberg S.C., Reasoner D.J. Heterotrophic plate count bacteria— what is their significance in drinking water? Int J Food Microbiol. 2004;92:265–274. doi: 10.1016/j.ijfoodmicro.2003.08.017. [DOI] [PubMed] [Google Scholar]
- American Pregnancy Association (2006) Available online at http://www. americanpregnancy.org/main/statistics.html.
- AWWA . Reinvesting in drinking water structure: dawn of the replacement era. Denver, CO: American Water Works Association; 2001. [Google Scholar]
- AWWA . Water Stats 2002 Distribution Survey CD-ROM. Denver, CO: American Water Works Association; 2003. [Google Scholar]
- AWWA and EES (2002) Finished water storage facilities. Available online at www. epa.gov/safewater/tcr/pdf/storage.pdf.
- AWWA and AWWARF . Water industry database: utility profiles. Denver, CO: American Water Works Association and American Water Works Association Research Foundation; 1992. [Google Scholar]
- AWWASC (2002) Deteriorating buried infrastructure management challenges and strategies. American Water Works Association Service Company, Inc. Available online at http://www.epa.gov/safewater/tcr/pdf/infrastructure.pdf.
- Barbeau B., Payment P., Coallier J., Clement B., Prevost M. Evaluating the risk of infection from the presence of Giardia and Cryptosporidium in drinking water. Quant Microbiol. 2000;2:37–54. [Google Scholar]
- Baribeau H., Pozos N.L., Boulos L., Crozes G.F., Gagnon G.A., Rutledge S., Skinner D., Hu Z., Hofmann R., Andrews R.C., Wojcicka L., Alam Z., Chauret C., Andrews S.A., Dumancis R., Warn E. Impact of Distribution System Water Quality on Disinfection Efficacy. Denver, CO: AWWARF; 2005. [Google Scholar]
- Barwick M.S., Levy D.A., Craun G.F., Beach M.J., Calderon R.L. Surveillance for waterborne-disease outbreaks—United States, 1997–1998. CDC, MMWR Surveillance Summaries. 2000;49(SS04):1–35. [PubMed] [Google Scholar]
- Bennett M. Bats and human emerging diseases. Epidemiol Infect. 2006;134:905–907. doi: 10.1017/S0950268806006674. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blackburn R.S., Craun G.F., Yoder J.S., Hill V., Calderon R.L., Chen N., Lee S.H., Levy D.A., Beach M.J. Surveillance for waterborne-disease outbreaks associated with drinking water—United States, 2001–2002. MMWR. 2004;53(SS–8):23–45. [PubMed] [Google Scholar]
- Borchardt M.A., Bertz P.D., Spencer S.K., Battigelli D.A. Incidence of enteric viruses in groundwater from household wells in Wisconsin. Appl Environ Microbiol. 2003;69:1172–1180. doi: 10.1128/AEM.69.2.1172-1180.2003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Borchardt M.A., Chyou P.H., De Vries E.O., Belongia E.A. Septic system density and infectious diarrhea in a defined population of children. Environ Health Perspect. 2003;111:742–748. doi: 10.1289/ehp.5914. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Borchardt M.A., Haas N.L., Hunt R.J. Vulnerability of drinking-water wells in La Crosse, Wisconsin, to enteric-virus contamination from surface water contributions. Appl Environ Microbiol. 2004;70:5937–5946. doi: 10.1128/AEM.70.10.5937-5946.2004. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Calderon R.G. Final report CR-813978-01-0. Cincinnati, OH: U.S. Environmental Protection Agency; 1991. Bacteria colonizing point of use, granular activated carbon filters and their relationship to human health. [Google Scholar]
- Calderon R.L. Microbes in drinking water: recent epidemiological research to assess waterborne risks. In: Craun G.F., Hauchman F.S., Robinson D.E., editors. Microbial Pathogens and Disinfection By-Products in Drinking Water. Health Effects and Management of Risks. Washington, DC: ILSI Press; 2001. pp. 137–147. [Google Scholar]
- Calderon RL (2004) Measuring benefits of drinking water technology: ten years of drinking water epidemiology. NEWWA Water Quality Symposium, May 20, 2004, Boxborough, MA.
- Calderon R.L., Craun G.F. Estimates of endemic waterborne risks from community-intervention studies. J Water Health. 2006;4(suppl 2):89–99. doi: 10.2166/wh.2006.019. [DOI] [PubMed] [Google Scholar]
- Camper A.K., Le Chevallier M.L., Broadaway S.C., McFeters G.A. Growth and persistence of pathogens on granular activated carbon. Appl Environ Microbiol. 1985;50:1178–1382. doi: 10.1128/aem.50.6.1378-1382.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CDC Surveillance for waterborne-disease outbreaks—United States, 1991–1992. Centers for Disease Control and Prevention. MMWR. 1993;42(SS05):1–22. [PubMed] [Google Scholar]
- CDC (2001) Helicobacter pylori: fact sheet for health care providers. Centers for Disease Control and Prevention. Available online at www.cdc.gov/ulcer/files/hpfacts.pdf.
- CDC (2005) National Estimates on Diabetes. National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention. http://www.cdc.gov/diabetes/pubs/estimates.htm#prev.
- CGER . Commission on Geosciences, Environment and Resources. Washington, DC: National Academies Press; 2001. Under the weather: climate, ecosystems, and infectious disease. [PubMed] [Google Scholar]
- Chen X., Keithly J.S., Paya C.V., LaRusso N.F. Cryptosporidiosis. N Engl J Med. 2002;346:1723–1731. doi: 10.1056/NEJMra013170. [DOI] [PubMed] [Google Scholar]
- Chaidez C., Gerba C. Comparison of the microbiologic quality of point-of-use (POU)-treated water and tap water. Int J Environ Health Res. 2004;14:253–260. doi: 10.1080/09603120410001725595. [DOI] [PubMed] [Google Scholar]
- Clark R.M., Geldreich E.E., Fox K.R., Rice W.W., Johnson C.H., Goodrich J.A., Barnick J.A., Abdesaken F. Tracking a Salmonella serovar typhimurium outbreak in Gideon, Missouri: Role of contamination propagation modeling. J Water Supply Res Tech Aqua. 1996;45:171–183. [Google Scholar]
- Colford J.M., Jr, Rees J.R., Wade T.J., Khalakdina A., Hilton J.F., Ergas I.J., Burns S., Benker A., Ma C., Bowen C., Mills D., Vugia D., Juranek D., Levy D. Participant blinding and gastrointestinal illness in a randomized, controlled trial of an inhome drinking water intervention. Emerg Infect Dis. 2002;8:29–36. doi: 10.3201/eid0801.001481. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Colford J.M., Jr, Wade T.J., Sandhu S.K., Wright C.C., Lee S., Shaw S., Fox K., Burns S., Benker A., Brookhart M.A., Van Der Laan M.J., Levy D.A. A randomized controlled trial of in-home drinking water intervention to reduce gastrointestinal illness. Am J Epidemiol. 2005;161:472–482. doi: 10.1093/aje/kwi067. [DOI] [PubMed] [Google Scholar]
- Colford J.M., Roy S., Beach M.J., Hightower A., Shaw S.E., Wade T.J. A review of household drinking water trials and an approach to the estimation of endemic waterborne gastroenteritis in the United States. J Water Health. 2006;4(suppl 2):71–88. doi: 10.2166/wh.2006.018. [DOI] [PubMed] [Google Scholar]
- Covello V.T., Merkhofer M.W. Risk Assessment Methods. New York: Plenum Press; 1993. [Google Scholar]
- Cox P., Griffith M., Angeles M., Deere D., Ferguson C. Concentration of pathogens and indicators in animal feces in the Sydney watershed. Appl Environ Microbiol. 2005;71:5929–5934. doi: 10.1128/AEM.71.10.5929-5934.2005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Craun G.F., Calderon R.L. Waterborne disease outbreaks caused by distribution system deficiencies. J Am Water Works Assoc. 2001;93:64–75. [Google Scholar]
- Craun G.F., Nwachuku N., Calderon R.L., Craun M.F. Outbreaks in drinkingwater systems, 1991–1998. J Environ Health. 2002;65:16–23. [PubMed] [Google Scholar]
- Craun M.F., Craun G.F., Calderon R.L., Beach M.J. Waterborne outbreaks in the United States. J Water Health. 2006;4(suppl 2):19–30. doi: 10.2166/wh.2006.016. [DOI] [PubMed] [Google Scholar]
- Curriero F.C., Patz J.A., Rose J.B., Lele S. The association between extreme precipitation and waterborne disease outbreaks in the United States, 1948–1994. Am J Public Health. 2001;91:1194–1199. doi: 10.2105/ajph.91.8.1194. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Deb A.K., Hasit Y.J., Grablutz F.M. Distribution System Performance Evaluation. Denver, CO: AWWARF; 1995. [Google Scholar]
- Edberg S.C., Allen M.J. Virulence and risk from drinking water of heterotrophic plate count bacteria in human population groups. Int J Food Microbiol. 2004;92:255–263. doi: 10.1016/j.ijfoodmicro.2003.08.012. [DOI] [PubMed] [Google Scholar]
- Edwards M, Marshall B, Zhang Y, Lee Y (2005) Unintended consequences of chloramine hit home. In: Proceedings of the WEF Disinfection Conference, Mesa, AZ.
- Egorov A., Ford T., Tereschenko A., Drizhd N., Segedevich I., Fourman V. Deterioration of drinking water quality in the distribution system and gastrointestinal morbidity in a Russian city. Int J Environ Health Res. 2002;12:221–233. doi: 10.1080/09603/202/000000989. [DOI] [PubMed] [Google Scholar]
- Elitsur Y., Short J.P., Neace C. Prevalence of Helicobacter pylori infection in children from urban and rural West Virginia. Dig Dis Sci. 1998;43:773–778. doi: 10.1023/a:1018866030977. [DOI] [PubMed] [Google Scholar]
- Fallacara D.M., Monahan C.M., Morishita T.Y., Bremen C.A., Back R.F. Survey of parasites and bacterial pathogens from free-living waterfowl in zoological settings. Avian Dis. 2004;48:759–767. doi: 10.1637/7185-032904R. [DOI] [PubMed] [Google Scholar]
- Flannery B, Gelling LB, Vugia DJ, Weintraub JM, Salerno JJ, Conroy MJ, Stevens VA, Rose CE, Moore MR, Fields BS, Besser RE (2006) Reducing Legionella colonization of water systems with monochloramine. Emerg Infect Dis. Available at http://www.cdc.gov/ncidod/EID/vol12no04/05-1101.htm. [DOI] [PMC free article] [PubMed]
- Fout G.S., Martinson B.C., Moyer M.W., Dahling D.R. A multiplex reverse transcription-PCR method for detection of human enteric viruses in groundwater. Appl Environ Microbiol. 2003;69:3158–3164. doi: 10.1128/AEM.69.6.3158-3164.2003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Frost F.J., Kunde T.R., Harder L., Muller T.I. Unpublished report. Albuquerque, NM: Lovelace Clinic Foundation; 2006. Preliminary Report—Northwest Epidemiological Enteric Disease Study. [Google Scholar]
- Gadgil A.J. Drinking water in developing countries. Annu Rev Energy Environ. 1998;23:253–286. [Google Scholar]
- Gerba CP (2003) Presentation at the National Science Foundation/Water Quality Center Bi-Annual meeting, December 2002, Tempe, AZ.
- Gerba C.P., Rose J.B., Haas C.N. Sensitive populations: who is at the greatest risk? Int J Food Microbiol. 1996;30:113–123. doi: 10.1016/0168-1605(96)00996-8. [DOI] [PubMed] [Google Scholar]
- Gerba C.P., Rose J.B., Haas C.N., Crabtree C.D. Waterborne rotavirus: a risk assessment. Water Res. 1996;30:2929–2940. [Google Scholar]
- Glynn M, Rhodes P (2005) Estimated HIV prevalence in the United States at the end of 2003. National HIV Prevention Conference, June 2005, Atlanta, GA.
- Goh S., Reacher M., Casemore D.P., Verlander N.Q., Charlett A., Chalmers R.M., Knowles M., Pennington A., Williams J., Osborn K., Richards S. Sporadic cryptosporidiosis decline after membrane filtration of public water supplies, England, 1996’2002. Emerg Infect Dis. 2005;11:251–259. doi: 10.3201/1102.040274. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Grigg N.S. Assessment and renewal of water distribution systems. J Am Water Works Assoc. 2005;97:58–68. [Google Scholar]
- Haas C. Benefits of using a disinfectant residual. J Am Water Works Assoc. 1999;90:65–67. [Google Scholar]
- Haas C.N., Trussell R.R. Framework for assessing reliability of multiple, independent barriers in potable water reuse. Water Sci Technol. 1998;38:1–8. [Google Scholar]
- Haas C.N., Rose J.B., Gerba C.P., Regli S. Risk assessment of virus in drinking water. Risk Anal. 1993;13:545–552. doi: 10.1111/j.1539-6924.1993.tb00013.x. [DOI] [PubMed] [Google Scholar]
- Haas C.N., Chitluru R.B., Gupta M., Pipes W.O., Burlingame G.A. Development of disinfection guidelines for the installation and replacement of water mains. Denver, CO: AWWARF; 1998. [Google Scholar]
- Hancock C.M., Rose J.B., Callahan M. Cryptosporidium and Giardia in U.S. groundwater. J Am Water Works Assoc. 1998;90(3):58–61. [Google Scholar]
- Hawkins M., DeLong S., Marcus R., Jones T., Shallow S., Morse D., McCombs K., Courtney A., Medus C., Shiferaw B., Imhoff B., the EIP FoodNet Working Group . Program and Abstracts of the International Conference on Emerging Infectious Diseases, Atlanta, GA. Alexandria, VA: American Society for Microbiology; 2002. The burden of diarrheal illness in FoodNet, 2000–2001 (abstract) [Google Scholar]
- Heirholzer J.C. Adenoviruses in the immunocompromised host. Clin Microbiol Rev. 1992;5:262–274. doi: 10.1128/cmr.5.3.262. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hellard M.E., Sinclair M.I., Forbes A.B., Fairley C.K. A randomized, blinded, controlled trial investigating the gastrointestinal health effects of drinking water quality. Environ Health Perspect. 2001;109:773–778. doi: 10.1289/ehp.01109773. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hellard M.E., Sinclair M.I., Dharmage S.C., Bailey J.F., Fairley C.K. The rate of gastroenteritis in a large city before and after chlorination. Int J Environ Health Res. 2002;12:355–360. doi: 10.1080/0960312021000056384. [DOI] [PubMed] [Google Scholar]
- Herbarth O., Krumbiegel P., Fritz G.J., Richter M., Schlink U., Müller D.M., Richter T. Helicobacter pylori prevalences and risk factors among school beginners in a German urban center and its rural county. Environ Health Perspect. 2001;109:573–577. doi: 10.1289/ehp.01109573. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Herrick D. Cross-connections and backflow. Water Well J. 1997;51:67–70. [Google Scholar]
- Imhoff B., Morse D., Shiferaw B., Hawkins M., Vugia D., Lance-Parker S., Hadler J., Medus C., Kennedy M., Moore M.R., Van Gilder T., Group F.W. Burden of self-reported acute diarrheal illness in FoodNet surveillance areas, 1998–1999. Clin Infect Dis. 2004;38(suppl 3):S219–S226. doi: 10.1086/381590. [DOI] [PubMed] [Google Scholar]
- James K.E., Block D.A., Lee K.K., Kraemer H.C., Fuller R.K. An index for assessing blindness in a multi-centre clinical trial: disulfiram for alcohol cessation: a VA cooperative study. Stat Med. 1996;15:1421–1434. doi: 10.1002/(SICI)1097-0258(19960715)15:13<1421::AID-SIM266>3.0.CO;2-H. [DOI] [PubMed] [Google Scholar]
- Jemal A., Murray T., Ward E., Samuels A., Tiwari R.C., Ghafoor A., Feuer E.J., Thun M.J. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10–30. doi: 10.3322/canjclin.55.1.10. [DOI] [PubMed] [Google Scholar]
- Jones T.F., McMillian M.B., Scallan E., Frenzen P.D., Cronquist A.B., Thomas S., Angulo F.J. A Population-Based Estimate of the Substantial Burden of Diarrheal Disease in the United States; FoodNet, 1996–2003. Centers for Disease Control and Prevention, Atlanta, GA. 2007;135:293–301. doi: 10.1017/S0950268806006765. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Karim M., Abbaszadegan M., LeChevallier M.W. Potential for pathogen intrusion during pressure transients. J Am Water Works Assoc. 2003;95:134–146. [Google Scholar]
- Kirmeyer G., Richards W., Smith C.D. An assessment of water distribution systems and associated research needs. Denver, CO: AWWARF; 1994. [Google Scholar]
- Kirmeyer G.K., Freidman M., Martel K., Howie D., LeChevallier M., Abbaszadegan M., Karim M., Funk J., Harbour J. Pathogen intrusion into the distribution system. Denver, CO: AWWARF; 2001. [Google Scholar]
- Korich D.G., Mead J.R., Madore M.S., Sinclair N.A., Sterling C.R. Effects of ozone, chlorine dioxide, chlorine, and chloramine on Cryptosporidium parvum oocyst viability. Appl Environ Microbiol. 1990;56:1423–1428. doi: 10.1128/aem.56.5.1423-1428.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kramer M.H., Herwaldt B.L., Calderon R.L., Juranek D.D. Surveillance for waterborne-disease outbreaks—United States, 1993–1994. CDC MMWR Surveillance Summaries. 1996;45(SS01):1–33. [PubMed] [Google Scholar]
- Kunde T.R., Frost F.J., Nelson L.S., Harter L., Craun M.F., Craun G.F., Calderon R.L. Community intervention study: Reduced gastrointestinal illness rates associated with improved water treatment. Albuquerque, NM: Lovelace Clinic Foundation; 2006. Estimates of endemic waterborne risks. [Google Scholar]
- Le Chevallier M.W., Gullick R.W., Karim M.R., Friedman M., Funk J.E. The potential for health risks from intrusion of contaminants into the distribution system from pressure transients. J Water Health. 2003;1:3–14. [PubMed] [Google Scholar]
- LeChevallier MW, Gullick RW, Karim M (2003b) The potential for health risks from intrusion of contaminants into the distribution system from pressure transients. Distribution system white paper. http://www.epa.gov/safewater/tcr/pdf/intrusion. pdf. [PubMed]
- Lee E.J., Schwab K.J. Deficiencies in drinking water distribution systems in developing countries. J Water Health. 2005;3:109–127. [PubMed] [Google Scholar]
- Lee S.H., Levy D.A., Craun G.F., Beach M.J., Calderon R.L. Surveillance for waterborne-disease outbreaks—United States, 1999–2000. CDC MMWR Surveillance Summaries. 2002;51(SS08):1–28. [PubMed] [Google Scholar]
- Lee J.J., Schwartz P., Sylvester P., Crane L., Haw J., Chang H., Kwon H.J. Impacts of Cross-Connections in North American Water Supplies. Denver, CO: AWWARF; 2003. [Google Scholar]
- Levy D.A., Bens M.S., Craun G.F., Calderon R.L., Herwaldt B.L. Surveillance for waterborne-disease outbreaks—United States, 1995—1996. CDC MMWR Surveillance Summaries. 1998;47(SS05):1–34. [PubMed] [Google Scholar]
- Lew J.F., Glass R.I., Gangarosa R.E., Cohen I.P., Bern C., Moe C.L. Diarrheal deaths in the United States, 1979–1987. A special problem for the elderly. JAMA. 1991;265:3280–3284. [PubMed] [Google Scholar]
- Liang J.L., Dziuban E.J., Craun G.F., Hill V., Moore M.R., Gelting R.J., Calderon R.L., Beach M.J., Roy S.L. Surveillance for waterborne disease and outbreaks associated with drinking water and water not intended for drinking—United States, 2003–2004. MMWR. 2006;55(12):31–65. [PubMed] [Google Scholar]
- Lindsay J.A. Chronic sequelae of food-borne disease. Emerg Infec Dis. 1997;3:443–452. doi: 10.3201/eid0304.970405. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mansfield L.S., Gajadhar A.A. Cyclospora cayetanensis, a food-and waterborne coccidian parasite. Vet Parasitol. 2004;126:73–90. doi: 10.1016/j.vetpar.2004.09.011. [DOI] [PubMed] [Google Scholar]
- McConnell S., Horrocks M., Sinclair M., Fairley C.K. Changes in the incidence of gastroenteritis and the implementation of public water treatment. Int J Environ Health Res. 2001;11:299–308. doi: 10.1080/09603120120070919. [DOI] [PubMed] [Google Scholar]
- Medema G.J., Teunis P.F., Havelaar A.H., Haas C.N. Assessment of the doseresponse relationship of Campylobacter jejuni. Int J Food Microbiol. 1996;30:101–111. doi: 10.1016/0168-1605(96)00994-4. [DOI] [PubMed] [Google Scholar]
- Messner M.J., Chappell C.L., Okhuysen P.C. Risk assessment for Cryptosporid- ium: a hierarchical Bayesian analysis of human dose response data. Water Res. 2001;35:3934–3940. doi: 10.1016/s0043-1354(01)00119-1. [DOI] [PubMed] [Google Scholar]
- Messner M., Shaw S., Regli S., Rotert K., Blank V., Soller J. An approach for developing a national estimate of waterborne disease due to drinking water and a national estimate model application. J Water Health. 2006;4(suppl 2):201–240. doi: 10.2166/wh.2006.024. [DOI] [PubMed] [Google Scholar]
- Morris R.D., Levin R. Estimating the incidence of waterborne infectious disease related to drinking water in the United States. In: Reichard E., Zapponi G., editors. Assessing and managing health risks from drinking water contamination: approaches and applications; Wallingford, UK: International Association of Hydrological Sciences; 1995. [Google Scholar]
- NRC . Drinking water distribution systems: assessing and reducing risks. National Research Council. Washington, DC: The National Academies Press; 2006. pp. 90–137. [Google Scholar]
- Nwachuku N., Gerba C.P. Health risks of enteric viral infections in children. Rev Environ Contam Toxicol. 2006;186:1–56. doi: 10.1007/0-387-32883-1_1. [DOI] [PubMed] [Google Scholar]
- Nwachuku N., Gerba C.P., Oswald A., Mashadi F.D. Comparative inactivation of adenovirus serotypes by UV light disinfection. Appl Environ Microbiol. 2005;71:5633–5636. doi: 10.1128/AEM.71.9.5633-5636.2005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Park S.R., Mackay W.G., Reid D.C. Helicobacter sp. recovered from drinking water biofilm sampled from a water distribution system. Water Res. 2001;35:1624–1626. doi: 10.1016/s0043-1354(00)00582-0. [DOI] [PubMed] [Google Scholar]
- Parkin R.T. Annual Meeting of the Society for Risk Analysis. Arlington, VA: Center for Risk Science and Public Health; 2000. Issues in modeling rare health events such as chronic sequelae associated with microbial pathogens. [Google Scholar]
- Payment P. Poor efficacy of residual chlorine disinfectant in drinking water to inactivate waterborne pathogens in distribution systems. Can J Microbiol. 1999;45:709–715. [PubMed] [Google Scholar]
- Payment P., Richardson L., Siemiatycki J., Dewar R., Edwardes M., Franco E. A randomized trial to evaluate the risk of gastrointestinal disease due to consumption of drinking water meeting current microbiological standards. Am J Public Health. 1991;81:703–708. doi: 10.2105/ajph.81.6.703. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Payment P., Siemiatycki J., Richardson L., Renaud G., Franco E., Prevost M. A prospective epidemiological study of gastrointestinal health effects due to the consumption of drinking water. Int J Environ Health Res. 1997;7:5–31. [Google Scholar]
- Pepper I.L., Rusin P., Quintanar D.R., Haney C., Josephson K.L., Gerba C.P. Tracking the concentration of heterotrophic plate count bacteria from the source to the consumer’s tap. J Food Microbiol. 2004;9:289–295. doi: 10.1016/j.ijfoodmicro.2003.08.021. [DOI] [PubMed] [Google Scholar]
- Pierson G., Martel K., Hill A., Burlingame G., Godfree A. Methods to prevent microbiological contamination associated with main rehabilitation and replacement. Denver, CO: AWWARF; 2001. [Google Scholar]
- Propato M., Uber J.G. Vulnerability of water distribution systems to pathogen intrusion: how effective is a disinfectant residual? Environ Sci Technol. 2004;38:3713–3722. doi: 10.1021/es035271z. [DOI] [PubMed] [Google Scholar]
- Pryor M., Springthorpe S., Riffard S., Brooks T., Huo Y., Davis G., Satter S.A. Investigation of opportunistic pathogens in municipal drinking water under different supply and treatment regimes. Water Sci Technol. 2004;50:83–90. [PubMed] [Google Scholar]
- Raina P.S., Pollari F.L., Teare G.F., Goss M.J., Barry D.A., Wilson J.B. The relationship between E. coli indicator bacteria in well-water and gastrointestinal illnesses in rural families. Can J Public Health. 1999;90:172–175. doi: 10.1007/BF03404501. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Regli S., Rose J.B., Haas C.N., Gerba C.P. Modeling the risk from Giardia and viruses in drinking water. J Am Water Works Assoc. 1991;19:76–84. [Google Scholar]
- Regli S.E., Berger P.S., Grubbs T.R. Control of drinking water pathogens and disinfection byproducts. In: Pontius F.W., editor. Drinking Water Regulation and Health. New York: Wiley; 2003. pp. 277–305. [Google Scholar]
- Rennecker J.L., Marinas B.J., Owens J.H., Rice E.W. Inactivation of Cryptosporidium parvum (oo)cysts with ozone. Water Res. 1999;33:2481–2488. [Google Scholar]
- Rollinger Y., Dott W. Survival of selected bacterial species in sterilized activated carbon filters and biological activated filters. Appl Environ Microbiol. 1987;53:777–781. doi: 10.1128/aem.53.4.777-781.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith H.V., Grimason A.M. The Handbook of Water and Wastewater Microbiology. London: Academic Press; 2003. Giardia and Cryptosporidium in water and wastewater; pp. 698–756. [Google Scholar]
- Snead M.C., Olivieri V.P., Kawata K., Kruse C.W. The effectiveness of chlorine residuals in inactivation of bacteria and viruses introduced by post-treatment contamination. Water Res. 1980;14:403–408. [Google Scholar]
- Stine S.W., Pepper I.L., Gerba C.P. Contribution of drinking water to the weekly intake of heterotrophic bacteria from diet in the United States. Water Res. 2005;39:257–263. doi: 10.1016/j.watres.2004.09.010. [DOI] [PubMed] [Google Scholar]
- Thomas K.M., Charron D.F., Waltner-Toews D., Schuster C., Maarouf A.R., Holt J.D. A role of high impact weather events in waterborne disease outbreaks in Canada, 1975–2001. Int J Environ Health Res. 2006;16:167–180. doi: 10.1080/09603120600641326. [DOI] [PubMed] [Google Scholar]
- Thurston-Enriquez J.A., Haas C.N., Jacangelo J., Riley K., Gerba C.P. Inactivation of feline calicivirus and adenovirus type 40 by UV radiation. Appl Environ Microbiol. 2003;69:577–582. doi: 10.1128/AEM.69.1.577-582.2003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tobin-DAngelo M.J., Blass M.A., del Rio C., Halvosa J.S., Blumberg H.M., Horsburgh C.R. Hospital water as a source of complex isolates in respiratory specimens. J Infect Dis. 2004;189:98–104. doi: 10.1086/380492. [DOI] [PubMed] [Google Scholar]
- Trussell R.R. Safeguarding distribution system integrity. J Am Water Works Assoc. 1999;91:46–54. [Google Scholar]
- US Census Bureau (2005) American Community Survey. Available at http://factfinder.census.gov.
- US Department of Health and Human Services . Health Resources and Services Administration. Rockville, MD: Healthcare Systems Bureau, Division of Transplantation; 2005. Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1995–2004. [Google Scholar]
- USEPA . EPA 816-F-01-001. Office of Water. Washington, DC: U.S. Environmental Protection Agency; 2001. Drinking Water Infrastructure Needs Survey. [Google Scholar]
- USEPA (2002) Potential contamination due to cross-connections and backflow and the associated health risks: An issues paper. EPA’s Office of Ground Water and Drinking Water. Cross-Connection Control. August 13, 2002. Available at http:// www.m_2.us/files/ccrwhite.pdf.
- USEPA (2004) USEPA claims to meet drinking water goals despite persistent data quality shortcomings. Report no. 2004-P-0008. Available online at www.epa.gov/ oig/reports/2004/20040305-2004-P-0008.pdf.
- USEPA . Prepublication of ground water rule federal register notice. national primary drinking water regulations: ground water rule. Washington, DC: U.S. Environmental Protection Agency; 2006. [Google Scholar]
- USEPA (2006b) Public Drinking Water Systems: Facts and Figures. Available at http://www.epa.gov/safewater/data/getdata.html.
- Vacrewijck M.J.M., Huys G., Palomino J.C., Swings J., Portaels F. Mycobacteria in drinking water distribution systems: ecology and significance for human health. FEMS Microbiol Rev. 2005;29:911–934. doi: 10.1016/j.femsre.2005.02.001. [DOI] [PubMed] [Google Scholar]
- Velkoff V.A., DeBarros K.A. 65+ in the United States: 2005. Current population reports. Washington, DC: U.S. Census Bureau, U.S. Government Printing Office; 2005. pp. 23–209. [Google Scholar]
- WQA Water Quality Association) The 2001 national consumer water quality survey. Lisle, IL: Water Quality Association; 2001. [Google Scholar]
- WQA Water Quality Association) Heterotrophic bacteria in drinking water from POU & POE devices. Lisle, IL: Water Quality Association; 2002. [Google Scholar]
- Westrell T., Bergstedt O., Stenstrom T.A., Ashbolt N.J. A theoretical approach to assess microbial risks due to failures in drinking water systems. Int J Environ Health Res. 2003;13:181–197. doi: 10.1080/0960312031000098080. [DOI] [PubMed] [Google Scholar]
- WHO/NSF (2003) HPC and drinking-water safety: the significance of heterotrophic plate counts for water quality and human health. Available at http://www.nsf.org/conference/hpc/hpc_proceedings.html.