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. 2006;581:277–280. doi: 10.1007/978-0-387-33012-9_46

Analysis of SARS-CoV Receptor Activity of ACE2 Orthologs

Emily R Olivieri 3, Lindsey K Heller 4, Laura Gillim-Ross 5, David E Wentworth 6
Editors: Stanley Perlman1, Kathryn V Holmes2
PMCID: PMC7123352  PMID: 17037542

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Contributor Information

Stanley Perlman, Email: Stanley-Perlman@uiowa.edu

Kathryn V. Holmes, Email: Kathryn.Holmes@ucHSC.edu

References

  • 1.Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003, World Health Organization, http://www.who.int/csr/sars/country/table2004_04_21/en/index.html, 2004.
  • 2.Li WH, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003;426:450–454. doi: 10.1038/nature02145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Holmes KV. In: Fields Virology. Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, editors. Philadelphia: Lippincott Williams & Wilkins; 2001. pp. 1187–1203. [Google Scholar]
  • 4.Guan Y, Zheng BJ, He YQ, et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science. 2003;302:276–278. doi: 10.1126/science.1087139. [DOI] [PubMed] [Google Scholar]
  • 5.Chen W, Yan M, Yang L, et al. SARS-associated coronavirus transmitted from human to pig. Emerg. Infect. Dis. 2005;11:446–448. doi: 10.3201/eid1103.040824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Wentworth DE, Gillim-Ross L, Espina N, Bernard KA. Mice susceptible to SARS coronavirus. Emerg. Infect. Dis. 2004;10:1293–1296. doi: 10.3201/eid1007.031119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Subbarao K, McAuliffe J, Vogel L, et al. Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice. J. Virol. 2004;78:3572–3577. doi: 10.1128/JVI.78.7.3572-3577.2004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Roberts A, Vogel L, Guarner J, et al. Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters. J. Virol. 2005;79:503–511. doi: 10.1128/JVI.79.1.503-511.2005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Jeffers SA, Tusell SM, Gillim-Ross L, et al. CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. USA. 2004;101:15748–15753. doi: 10.1073/pnas.0403812101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Li W, Zhang C, Sui J, et al. Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J. 2005;24:1634–1643. doi: 10.1038/sj.emboj.7600640. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Gillim-Ross L, Taylor J, Scholl DR, et al. Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR. J. Clin. Microbiol. 2004;42:3196–3206. doi: 10.1128/JCM.42.7.3196-3206.2004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12.Towler P, Staker B, Prasad SG, et al. ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis. J. Biol. Chem. 2004;279:17996–18007. doi: 10.1074/jbc.M311191200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Cn3D 4.1, National Center for Biotechnology Information, http://www.ncbi.nlm.nih.gov, 2005.
  • 14.Wentworth DE, Holmes KV. Molecular determinants of species specificity in the coronavirus receptor aminopeptidase N (CD13): influence of N-linked glycosylation. J. Virol. 2001;75:9741–9752. doi: 10.1128/JVI.75.20.9741-9752.2001. [DOI] [PMC free article] [PubMed] [Google Scholar]

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