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Stanley Perlman, Email: Stanley-Perlman@uiowa.edu
Kathryn V. Holmes, Email: Kathryn.Holmes@ucHSC.edu
References
- 1.Kim JC, Spence RA, Currier PF, Lu X, Denison MR. Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d. Virology. 1995;208:1–8. doi: 10.1006/viro.1995.1123. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Harcourt BH, Jukneliene D, Kanjanahaluethai A, Bechill J, Severson KM, Smith CM, Rota PA, Baker SC. Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity. J. Virol. 2004;78:13600–13612. doi: 10.1128/JVI.78.24.13600-13612.2004. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Barretto, N., D. Jukneliene, K. Ratia, Z. Chen, A.D. Mesecar and S.C. Baker. The papain-like protease of Severe Acute Respiratory Syndrome (SARS) coronavirus has deubiquitinating activity. J. Virol. 79: 15189–15198. [DOI] [PMC free article] [PubMed]
- 4.Herold J, Siddell SG, Gorbalenya AE. A human RNA viral cysteine proteinase that depends on a unique Zn2+ binding finger connecting the two domains of a papain-like fold. J. Biol. Chem. 1999;274:14918–14925. doi: 10.1074/jbc.274.21.14918. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Johnston SC, Larsen CN, Cook WJ, Wilkinson KD, Hill CP. Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution. EMBO J. 1997;16:3787–3796. doi: 10.1093/emboj/16.13.3787. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Sulea T, Lindner HA, Purisima EO, Menard R. Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease? J. Virol. 2005;79:4550–4551. doi: 10.1128/JVI.79.7.4550-4551.2005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Hu M, Li P, Li M, Li W, Yao T, Wu JW, Gu W, Cohen RE, Shi Y. Crystal structure of a UBP-family deubiquitinating enzyme in isolation and complex with ubiquitin aldehyde. Cell. 2002;111:1041–1054. doi: 10.1016/S0092-8674(02)01199-6. [DOI] [PubMed] [Google Scholar]