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. 2004 Oct 29;225(4):1127–1130. doi: 10.1016/0022-2836(92)90110-6

Preliminary X-ray crystallographic analysis of intercellular adhesion molecule-1

Prasanna R Kolatkar 1, Marcos A Oliveira 1, Michael G Rossmann 1, Arthur H Robbins 2, Suresh K Katti 2, Helana Hoover-Litty 3, Carla Forte 3, Jeffrey M Greve 3, Alan McClelland 3, Norman H Olson 1
PMCID: PMC7127300  PMID: 1351949

Abstract

Crystals of the two ammo-terminal domains of intercellular adhesion molecule-1, the receptor for the major group of human rhinovirus serotypes, diffract to 3.0 Å resolution. The crystals are trigonal in space group P3121 or P3221 with cell dimensions of a = b = 55.7 Å, c = 166.3 Å, with probably six molecules per unit cell.

Keywords: ICAM-1, crystals, rhinovirus receptor, electron microscopy, X-ray diffraction

Abbreviations: ICAM-1, intracellular adhesion molecule-1; HRV, human rhinovirus; LFA-1, lymphocyte function-associated antigen-1; HIV, human immunodeficiency virus

Footnotes

These studies were supported by National Institutes of Health grants to M.G.R. and Timothy S. Baker and a Lucille P. Markey grant for the expansion of structural studies at Purdue University.

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